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Soledad Matus

Explore the profile of Soledad Matus including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 4211
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Recent Articles
1.
Falcon P, Brito A, Escandon M, Roa J, Martinez N, Tapia-Godoy A, et al.
Int J Mol Sci . 2025 Feb; 26(4). PMID: 40004088
Under conditions of amino acid deficiency, mammalian cells activate a nutrient-sensing kinase known as general control nonderepressible 2 (GCN2). The activation of GCN2 results in the phosphorylation of the alpha...
2.
Nunez M, Carvajal P, Aguilera S, Barrera M, Matus S, Couto A, et al.
JCI Insight . 2024 Oct; 9(22). PMID: 39388276
Sjögren's disease is a chronic autoimmune disease characterized by symptoms of oral and ocular dryness and extraglandular manifestations. Mouth dryness is not only due to reduced saliva volume, but also...
3.
Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, et al.
Genes Dev . 2024 Sep; 38(15-16):785. PMID: 39299905
No abstract available.
4.
Carvajal P, Bahamondes V, Jara D, Castro I, Matus S, Aguilera S, et al.
Front Med (Lausanne) . 2023 Apr; 10:1118703. PMID: 37035319
Introduction: Primary Sjögren's syndrome (SS) is an autoimmune exocrinopathy that affects the structure and function of salivary and lachrymal glands. Labial salivary gland (LSG) acinar cells from SS patients lose...
5.
Martinez N, Gomez F, Matus S
Front Aging Neurosci . 2021 May; 13:638208. PMID: 33994991
There is a growing evidence describing a decline in adaptive homeostasis in aging-related diseases affecting the central nervous system (CNS), many of which are characterized by the appearance of non-native...
6.
Vidal R, Sepulveda D, Troncoso-Escudero P, Garcia-Huerta P, Gonzalez C, Plate L, et al.
Mol Ther . 2021 Feb; 29(5):1862-1882. PMID: 33545358
Alteration to endoplasmic reticulum (ER) proteostasis is observed in a variety of neurodegenerative diseases associated with abnormal protein aggregation. Activation of the unfolded protein response (UPR) enables an adaptive reaction...
7.
Barrera M, Aguilera S, Castro I, Matus S, Carvajal P, Molina C, et al.
Rheumatology (Oxford) . 2020 Nov; 60(4):1951-1962. PMID: 33216905
Objective: Altered homeostasis of salivary gland (SG) epithelial cells in Sjögren's syndrome (SS) could be the initiating factor that leads to inflammation, secretory dysfunction and autoimmunity. Autophagy is an important...
8.
Montoya A, Elgueta D, Campos J, Chovar O, Falcon P, Matus S, et al.
J Neuroinflammation . 2019 Dec; 16(1):258. PMID: 31810491
Background: Neuroinflammation constitutes a pathogenic process leading to neurodegeneration in several disorders, including Alzheimer's disease, Parkinson's disease (PD) and sepsis. Despite microglial cells being the central players in neuroinflammation, astrocytes...
9.
Falcon P, Escandon M, Brito A, Matus S
Oxid Med Cell Longev . 2019 Jun; 2019:5730532. PMID: 31249645
Aging is a complex process in which the accumulation of molecular, cellular, and organism dysfunction increases the probability of death. Several pieces of evidence have revealed a contribution of stress...
10.
Matamala J, Arias-Carrasco R, Sanchez C, Uhrig M, Bargsted L, Matus S, et al.
Neurobiol Aging . 2018 Feb; 64:123-138. PMID: 29458840
The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related proteins...