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Sokna Ly

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Articles 9
Citations 41
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Recent Articles
1.
Fathi P, Alfonso A, Yek C, Putman Z, Drew M, Esposito D, et al.
Adv Sci (Weinh) . 2024 Oct; 12(1):e2403503. PMID: 39471070
Dynamic pathogen exposure may impact the immunological response to SARS-CoV-2 (SCV2). One potential explanation for the lack of severe SCV2-related morbidity and mortality in Southeast Asia is prior exposure to...
2.
Yek C, Lon C, Chea S, Lay S, Oum M, Tang G, et al.
J Infect Dis . 2024 Aug; PMID: 39163245
Background: Antimicrobial resistance (AMR) surveillance in low- and middle-income countries (LMICs) often relies on poorly resourced laboratory processes. Centralized sequencing was combined with cloud-based, open-source bioinformatics solutions for national AMR...
3.
Pacheco A, Chea S, Saunders H, Ly S, Sath R, Tim R, et al.
Am J Trop Med Hyg . 2024 Jun; 111(2):277-280. PMID: 38889712
In resource-scarce settings, melioidosis is associated with up to 80% mortality. Studies of melioidosis in Cambodia report primarily on pediatric populations with localized infection; however, literature describing Cambodian adults with...
4.
Chea S, Willen L, Nhek S, Ly P, Tang K, Oristian J, et al.
Front Immunol . 2024 May; 15:1368066. PMID: 38751433
Introduction: are the most prolific mosquito vectors in the world. Found on every continent, they can effectively transmit various arboviruses, including the dengue virus which continues to cause outbreaks worldwide...
5.
Chea S, Willen L, Nhek S, Ly P, Tang K, Oristian J, et al.
medRxiv . 2024 Feb; PMID: 38318204
Introduction: are the most prolific mosquito vectors in the world. Found on every continent, they can effectively transmit various arboviruses, including the dengue virus which continues to cause outbreaks worldwide...
6.
Guerrero D, Vo H, Lon C, Bohl J, Nhik S, Chea S, et al.
Nat Commun . 2022 Nov; 13(1):7036. PMID: 36396947
Mosquito-borne viruses are a growing global threat. Initial viral inoculation occurs in the skin via the mosquito 'bite', eliciting immune responses that shape the establishment of infection and pathogenesis. Here...
7.
Bohl J, Lay S, Chea S, Ahyong V, Parker D, Gallagher S, et al.
Proc Natl Acad Sci U S A . 2022 Mar; 119(11):e2115285119. PMID: 35238677
SignificanceMetagenomic pathogen sequencing offers an unbiased approach to characterizing febrile illness. In resource-scarce settings with high biodiversity, it is critical to identify disease-causing pathogens in order to understand burden and...
8.
Vanachayangkul P, Sea D, Wojnarski M, Sok S, Kodchakorn C, Ta-Aksorn W, et al.
Antimicrob Agents Chemother . 2022 Jan; 66(3):e0182121. PMID: 34978892
The active metabolites of primaquine, in particular 5-hydroxyprimaquine, likely responsible for the clearance of dormant hypnozoites, are produced through the hepatic CYP450 2D6 (CYP2D6) enzymatic pathway. With the inherent instability...
9.
Wojnarski B, Lon C, Sea D, Sok S, Sriwichai S, Chann S, et al.
PLoS One . 2020 Feb; 15(1):e0228207. PMID: 32004348
Background: Primaquine is an approved radical cure treatment for Plasmodium vivax malaria but treatment can result in life-threatening hemolysis if given to a glucose-6-phosphate dehydrogenase deficient (G6PDd) patient. There is...