Sofie Nystrom
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Explore the profile of Sofie Nystrom including associated specialties, affiliations and a list of published articles.
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1066
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Recent Articles
1.
Westermark G, Nystrom E, Nystrom S, Nilsson K, Hammarstrom P, Westermark P
Sci Rep
. 2025 Jan;
15(1):3684.
PMID: 39881136
The existence of transmissible amyloid fibril strains has long intrigued the scientific community. The strain theory originates from prion disorders, but here, we provide evidence of strains in systemic amyloidosis....
2.
Parvin F, Larsson J, Jackson W, Nystrom S, Hammarstrom P
J Mol Biol
. 2024 Dec;
437(3):168923.
PMID: 39725269
Aβ-amyloid plaques and cerebral amyloid angiopathy (CAA) in the brain are pathological hallmarks of Alzheimer's disease (AD) and vascular dementia. The spreading of Aβ amyloidosis in the brain appears to...
3.
Klingstedt T, Shirani H, Parvin F, Nystrom S, Hammarstrom P, Graff C, et al.
J Biol Chem
. 2024 Nov;
301(1):108032.
PMID: 39615691
Different types of deposits comprised of amyloid-β (Aβ) peptides are one of the pathological hallmarks of Alzheimer's disease (AD) and novel methods that enable identification of a diversity of Aβ...
4.
Johansson L, Sandberg A, Nystrom S, Hammarstrom P, Hallbeck M
J Neurochem
. 2024 Aug;
168(9):3308-3322.
PMID: 39133499
The amyloid β (Aβ) peptide has a central role in Alzheimer's disease (AD) pathology. The peptide length can vary between 37 and 49 amino acids, with Aβ1-42 being considered the...
5.
Bonhenry D, Charnley M, Goncalves J, Hammarstrom P, Heneka M, Itzhaki R, et al.
Lancet Neurol
. 2024 May;
23(6):562-563.
PMID: 38760096
No abstract available.
6.
Parvin F, Haglund S, Wegenast-Braun B, Jucker M, Saito T, Saido T, et al.
ACS Chem Neurosci
. 2024 Apr;
15(10):2058-2069.
PMID: 38652895
Amyloid plaques composed of fibrils of misfolded Aβ peptides are pathological hallmarks of Alzheimer's disease (AD). Aβ fibrils are polymorphic in their tertiary and quaternary molecular structures. This structural polymorphism...
7.
Hammarstrom P, Nystrom S
Prion
. 2023 Mar;
17(1):82-104.
PMID: 36998202
The crosstalk between viral infections, amyloid formation and neurodegeneration has been discussed with varying intensity since the last century. Several viral proteins are known to be amyloidogenic. Post-acute sequalae (PAS)...
8.
Lerouge F, Ong E, Rositi H, Mpambani F, Berner L, Bolbos R, et al.
Nanomedicine (Lond)
. 2023 Mar;
17(29):2173-2187.
PMID: 36927004
To propose a new multimodal imaging agent targeting amyloid-β (Aβ) plaques in Alzheimer's disease. A new generation of hybrid contrast agents, based on gadolinium fluoride nanoparticles grafted with a pentameric...
9.
Jiang R, Smailovic U, Haytural H, Tijms B, Li H, Haret R, et al.
Acta Neuropathol Commun
. 2022 Jul;
10(1):96.
PMID: 35787306
Cerebrospinal fluid (CSF) biomarkers play an important role in diagnosing Alzheimer's disease (AD) which is characterized by amyloid-β (Aβ) amyloidosis. Here, we used two App knock-in mouse models, App and...
10.
Larsson J, Nystrom S, Hammarstrom P
Front Neurosci
. 2022 Jun;
16:902600.
PMID: 35769706
Neurodegenerative diseases (NDs) are associated with accumulated misfolded proteins (MPs). MPs oligomerize and form multiple forms of amyloid fibril polymorphs that dictate fibril propagation and cellular dysfunction. Protein misfolding processes...