Wojciech Michno
Overview
Explore the profile of Wojciech Michno including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
345
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Recent Articles
1.
Koutarapu S, Ge J, Dulewicz M, Srikrishna M, Szadziewska A, Wood J, et al.
bioRxiv
. 2024 Jun;
PMID: 38895368
Amyloid plaque deposition is recognized as the primary pathological hallmark of Alzheimer's disease(AD) that precedes other pathological events and cognitive symptoms. Plaque pathology represents itself with an immense polymorphic variety...
2.
Michno W, Bowman A, Jha D, Minta K, Ge J, Koutarapu S, et al.
ACS Chem Neurosci
. 2024 Feb;
15(4):877-888.
PMID: 38299453
Lipid dysregulations have been critically implicated in Alzheimer's disease (AD) pathology. Chemical analysis of amyloid-β (Aβ) plaque pathology in transgenic AD mouse models has demonstrated alterations in the microenvironment in...
3.
Qu F, Brough S, Michno W, Madubata C, Hartmann G, Puno A, et al.
Nat Cell Biol
. 2023 Oct;
25(10):1506-1519.
PMID: 37783795
Brain metastases represent an important clinical problem for patients with small-cell lung cancer (SCLC). However, the mechanisms underlying SCLC growth in the brain remain poorly understood. Here, using intracranial injections...
4.
Wehrli P, Ge J, Michno W, Koutarapu S, Dreos A, Jha D, et al.
JACS Au
. 2023 Apr;
3(3):762-774.
PMID: 37006756
We present a novel, correlative chemical imaging strategy based on multimodal matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI), hyperspectral microscopy, and spatial chemometrics. Our workflow overcomes challenges associated with...
5.
Hsu J, Fatuzzo N, Weng N, Michno W, Dong W, Kienle M, et al.
J Biol Chem
. 2023 Jan;
299(2):102848.
PMID: 36587768
In eukaryotes, carnitine is best known for its ability to shuttle esterified fatty acids across mitochondrial membranes for β-oxidation. It also returns to the cytoplasm, in the form of acetyl-L-carnitine...
6.
Michno W, Koutarapu S, Camacho R, Toomey C, Stringer K, Minta K, et al.
J Neurochem
. 2022 Sep;
163(3):233-246.
PMID: 36102248
Familial British dementia (FBD) and familial Danish dementia (FDD) are autosomal dominant forms of dementia caused by mutations in the integral membrane protein 2B (ITM2B, also known as BRI2) gene....
7.
Koutarapu S, Ge J, Jha D, Blennow K, Zetterberg H, Lashley T, et al.
Brain Connect
. 2022 Sep;
13(5):297-306.
PMID: 36074939
Alzheimer's disease (AD) is the most common neurodegenerative disease. The predominantly sporadic form of AD is age-related, but the underlying pathogenic mechanisms remain not fully understood. Current efforts to combat...
8.
Kushnir M, Michno W, Rockwood A, Blennow K, Strathmann F, Hanrieder J
Clin Mass Spectrom
. 2021 Dec;
14 Pt B:124-129.
PMID: 34917769
Background: Parathyroid hormone-related protein (PTHrP) is involved in intracellular calcium regulation, neural cell proliferation and synaptic transmission. To date, no studies have been performed to evaluate the potential of PTHrP...
9.
Michno W, Wehrli P, Koutarapu S, Marsching C, Minta K, Ge J, et al.
J Neurochem
. 2021 Dec;
160(4):482-498.
PMID: 34882796
Understanding of Alzheimer's disease (AD) pathophysiology requires molecular assessment of how key pathological factors, specifically amyloid β (Aβ) plaques, influence the surrounding microenvironment. Here, neuronal lipids have been implicated in...
10.
Bergstrom P, Trybala E, Eriksson C, Johansson M, Satir T, Widehn S, et al.
Viruses
. 2021 Oct;
13(10).
PMID: 34696502
Herpes simplex virus 1 (HSV-1) and 2 (HSV-2) can infect the central nervous system (CNS) with dire consequences; in children and adults, HSV-1 may cause focal encephalitis, while HSV-2 causes...