Alexander Sandberg
Overview
Explore the profile of Alexander Sandberg including associated specialties, affiliations and a list of published articles.
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11
Citations
61
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Recent Articles
1.
Johansson L, Sandberg A, Nystrom S, Hammarstrom P, Hallbeck M
J Neurochem
. 2024 Aug;
168(9):3308-3322.
PMID: 39133499
The amyloid β (Aβ) peptide has a central role in Alzheimer's disease (AD) pathology. The peptide length can vary between 37 and 49 amino acids, with Aβ1-42 being considered the...
2.
Schaake R, Leopold I, Sandberg A, Zenk B, Shafer L, Yu D, et al.
J Vasc Interv Radiol
. 2024 Mar;
35(6):825-833.
PMID: 38484911
Purpose: To assess the analgesic and anxiolytic effects of virtual reality (VR) augmentation in patients undergoing peripherally inserted central catheter (PICC) placement or fine-needle aspiration thyroid biopsy. Materials And Methods:...
3.
Lindberg A, Knight A, Sohn D, Rakos L, Tong J, Radelet A, et al.
ACS Chem Neurosci
. 2021 Jan;
12(4):596-602.
PMID: 33497190
CBD-2115 was selected from a library of 148 compounds based on a pyridinyl-indole scaffold as a first-in-class 4R-tau radiotracer. In vitro binding assays showed [H]CBD-2115 had a value of 6.9...
4.
Sandberg A, Ling H, Gearing M, Dombroski B, Cantwell L, RBibo L, et al.
Neurobiol Dis
. 2020 Sep;
146:105079.
PMID: 32961270
Microtubule Associated Protein Tau (MAPT) forms proteopathic aggregates in several diseases. The G273R tau mutation, located in the first repeat region, was found by exome sequencing in a patient who...
5.
Zhang J, Sandberg A, Wu X, Nystrom S, Lindgren M, Konradsson P, et al.
ACS Omega
. 2019 Aug;
2(8):4693-4704.
PMID: 31457755
It was previously reported that two naphthyl-based -stilbene probes, ()-4-(2-(naphthalen-1-yl)vinyl)benzene-1,2-diol () and ()-4-(2-(naphthalen-2-yl)vinyl)benzene-1,2-diol (), can bind to both native transthyretin (TTR) and misfolded protofibrillar TTR at physiological concentrations, displaying distinct...
6.
Jonson M, Nystrom S, Sandberg A, Carlback M, Michno W, Hanrieder J, et al.
Amyloid
. 2019 Jul;
26(sup1):136-137.
PMID: 31343327
No abstract available.
7.
Zhang J, Konsmo A, Sandberg A, Wu X, Nystrom S, Obermuller U, et al.
J Med Chem
. 2019 Feb;
62(4):2038-2048.
PMID: 30707834
A fluorescent bis-styryl-benzothiadiazole (BTD) with carboxylic acid functional groups (X-34/Congo red analogue) showed lower binding affinity toward Aβ1-42 and Aβ1-40 fibrils than its neutral analogue. Hence, variable patterns of neutral...
8.
Zhang J, Wang J, Sandberg A, Wu X, Nystrom S, LeVine 3rd H, et al.
Chemphyschem
. 2018 Sep;
19(22):3001-3009.
PMID: 30183138
Two analogues to the fluorescent amyloid probe 2,5-bis(4'-hydroxy-3'-carboxy-styryl)benzene (X-34) were synthesized based on the trans-stilbene pyrene scaffold (Py1SA and Py2SA). The compounds show strikingly different emission spectra when bound to...
9.
Sandberg A, Nystrom S
Methods Mol Biol
. 2018 Jun;
1779:147-166.
PMID: 29886532
Protein misfolding, aggregation, and amyloid formation is involved in a large number of diseases. Recombinantly expressed proteins to study the amyloid fibril formation process are important for mechanistic studies. We...
10.
Jonson M, Nystrom S, Sandberg A, Carlback M, Michno W, Hanrieder J, et al.
Cell Chem Biol
. 2018 Apr;
25(5):595-610.e5.
PMID: 29657084
The basis for selective vulnerability of certain cell types for misfolded proteins (MPs) in neurodegenerative diseases is largely unknown. This knowledge is crucial for understanding disease progression in relation to...