Smita K Nair
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Explore the profile of Smita K Nair including associated specialties, affiliations and a list of published articles.
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76
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2396
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Recent Articles
1.
Brown M, DAnniballe V, Boczkowski D, Kandadi H, Sheikh N, Kornahrens Jr W, et al.
Cancer Res Commun
. 2024 Sep;
4(10):2724-2733.
PMID: 39320053
Significance: The identification of factors that determine successful cancer immunotherapy, particularly in refractory tumor types like mCRPC, is urgently needed: both to identify patients that may benefit from such therapies...
2.
Sayour E, Boczkowski D, Mitchell D, Nair S
Nat Rev Clin Oncol
. 2024 May;
21(7):489-500.
PMID: 38760500
mRNA vaccines have been revolutionary in terms of their rapid development and prevention of SARS-CoV-2 infections during the COVID-19 pandemic, and this technology has considerable potential for application to the...
3.
McCutcheon S, Swartz A, Brown M, Barrera A, McRoberts Amador C, Siklenka K, et al.
Nat Genet
. 2023 Nov;
55(12):2211-2223.
PMID: 37945901
Clinical response to adoptive T cell therapies is associated with the transcriptional and epigenetic state of the cell product. Thus, discovery of regulators of T cell gene networks and their...
4.
Eckhoff A, Brown M, Landa K, Naqvi I, Holl E, Boczkowski D, et al.
Front Immunol
. 2023 Aug;
14:1116034.
PMID: 37575220
Background: Monocytes and monocyte-derived tumor infiltrating cells have been implicated in the immunosuppression and immune evasion associated with pancreatic adenocarcinoma (PDAC). Yet, precisely how monocytes in the periphery and tumor...
5.
Brown M, Beasley G, McKay Z, Yang Y, Desjardins A, Randazzo D, et al.
J Immunother Cancer
. 2023 Apr;
11(4).
PMID: 37072349
Background: Antitumor mechanisms of CD4 T cells remain crudely defined, and means to effectively harness CD4 T-cell help for cancer immunotherapy are lacking. Pre-existing memory CD4 T cells hold potential...
6.
Parker S, McDowall C, Sanchez-Perez L, Osorio C, Duncker P, Briley A, et al.
Sci Transl Med
. 2023 Feb;
15(682):eabn5649.
PMID: 36753564
D2C7-immunotoxin (IT), a dual-specific IT targeting wild-type epidermal growth factor receptor (EGFR) and mutant EGFR variant III (EGFRvIII) proteins, demonstrates encouraging survival outcomes in a subset of patients with glioblastoma....
7.
Mohan A, Olson L, Naqvi I, Morrison S, Kraft B, Chen L, et al.
Crit Care Explor
. 2022 Dec;
4(12):e0799.
PMID: 36506827
Design: Flow cytometry of fresh blood and multiplexed inflammatory chemokine measurements of sera were performed on samples collected longitudinally from our cohort. Aggregate impact of comorbid conditions was calculated with...
8.
Liu Y, Chorniak E, Odion R, Etienne W, Nair S, Maccarini P, et al.
Nanophotonics
. 2022 Nov;
10(12):3295-3302.
PMID: 36405500
Cancer is the second leading cause of death and there is an urgent need to improve cancer management. We have developed an innovative cancer therapy named Synergistic Immuno Photothermal Nanotherapy...
9.
Gilboa E, Boczkowski D, Nair S
Nucleic Acid Ther
. 2022 Nov;
32(6):449-456.
PMID: 36346283
The success of mRNA vaccines against COVID-19 is nothing short of a medical revolution. Given its chemical lability the use of mRNA as a therapeutic has been counterintuitive and met...
10.
Nief C, Swartz A, Chelales E, Sheu L, Crouch B, Ramanujam N, et al.
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230591
Ethanol ablation is a minimally invasive, cost-effective method of destroying tumor tissue through an intratumoral injection of high concentrations of cytotoxic alcohol. Ethyl-cellulose ethanol (ECE) ablation, a modified version of...