Sinem Karaman
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Explore the profile of Sinem Karaman including associated specialties, affiliations and a list of published articles.
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45
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2945
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Recent Articles
1.
Karaman S, Lehti S, Zhang C, Taskinen M, Kakela R, Mardinoglu A, et al.
FASEB J
. 2024 Oct;
38(20):e70097.
PMID: 39394863
Secondary lymphedema (LE) following breast cancer-related surgery is a life-long complication, which currently has no cure. LE induces significant regional adipose tissue deposition, requiring liposuction as a treatment. Here, we...
2.
Antila S, Chilov D, Nurmi H, Li Z, Nasi A, Gotkiewicz M, et al.
Nat Cardiovasc Res
. 2024 Aug;
3:474-491.
PMID: 39087029
Discovery of meningeal lymphatic vessels (LVs) in the dura mater, also known as dural LVs (dLVs) that depend on vascular endothelial growth factor C expression, has raised interest in their...
3.
Rannikko J, Verlingue L, de Miguel M, Pasanen A, Robbrecht D, Skytta T, et al.
Cell Rep Med
. 2023 Dec;
4(12):101307.
PMID: 38056464
Macrophage Clever-1 contributes to impaired antigen presentation and suppression of anti-tumor immunity. This first-in-human trial investigates the safety and tolerability of Clever-1 blockade with bexmarilimab in patients with treatment-refractory solid...
4.
Alve S, Gramolelli S, Jukonen J, Juteau S, Pink A, Manninen A, et al.
JCI Insight
. 2023 Nov;
9(1).
PMID: 37971882
Despite strong indications that interactions between melanoma and lymphatic vessels actively promote melanoma progression, the molecular mechanisms are not yet completely understood. To characterize molecular factors of this crosstalk, we...
5.
Anisimov A, Fang S, Hemanthakumar K, Ord T, Van Avondt K, Chevre R, et al.
Nat Cardiovasc Res
. 2023 Jul;
2(3):307-321.
PMID: 37476204
Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites,...
6.
Paavonsalo S, Subashi Y, Lackman M, Karaman S
STAR Protoc
. 2023 May;
4(2):102310.
PMID: 37182207
The small intestine is an excellent model for studying changes in vasculature in response to different diseases or gene deletions. Here, we present a protocol for whole-mount immunofluorescence staining of...
7.
Li Z, Antila S, Nurmi H, Chilov D, Korhonen E, Fang S, et al.
Sci Immunol
. 2023 Apr;
8(82):eabq0375.
PMID: 37058549
The recent discovery of lymphatic vessels (LVs) in the dura mater, the outermost layer of meninges around the central nervous system (CNS), has opened a possibility for the development of...
8.
Lackman M, Subashi Y, Karaman S
Curr Opin Hematol
. 2022 Feb;
29(3):144-150.
PMID: 35220323
Purpose Of Review: Lymphatic vessels are found in most tissues, with the exception of the cornea and the central nervous system. Tissues that have high exposure to antigens, such as...
9.
Karaman S, Paavonsalo S, Heinolainen K, Lackman M, Ranta A, Hemanthakumar K, et al.
J Exp Med
. 2022 Jan;
219(3).
PMID: 35050301
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are quintessential for the development and maintenance of blood and lymphatic vessels. However, genetic interactions between the VEGFRs are poorly understood....
10.
Yamashita M, Niisato M, Kawasaki Y, Karaman S, Robciuc M, Shibata Y, et al.
Eur Respir J
. 2021 Aug;
59(4).
PMID: 34446463
Background: Successful recovery from acute lung injury requires inhibition of neutrophil influx and clearance of apoptotic neutrophils. However, the mechanisms underlying recovery remain unclear. We investigated the ameliorative effects of...