Sinead M Miggin
Overview
Explore the profile of Sinead M Miggin including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
468
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Recent Articles
21.
Miggin S, Kinsella B
Mol Pharmacol
. 2002 Mar;
61(4):817-31.
PMID: 11901221
Thromboxane A(2) (TXA(2)) stimulates mitogenic growth of vascular smooth muscle. In humans, TXA(2) signals through two TXA(2) receptor (TP) isoforms, termed TPalpha and TPbeta. To investigate the mechanism of TXA(2)-mediated...
22.
Miggin S, Lawler O, Kinsella B
Eur J Biochem
. 2002 Mar;
269(6):1714-25.
PMID: 11895442
In the current study, we have established that the human (h) prostacyclin receptor (IP) is isoprenylated in whole cells. Through site directed mutagenesis and generation of the isoprenylation defective hIPSSLC,...