Jakub Siednienko
Overview
Explore the profile of Jakub Siednienko including associated specialties, affiliations and a list of published articles.
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30
Citations
305
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Recent Articles
1.
Krotofil M, Tota M, Siednienko J, Donizy P
Cancers (Basel)
. 2024 Oct;
16(20).
PMID: 39456632
The capacity of cancer cells to migrate from a primary tumor, disseminate throughout the body, and eventually establish secondary tumors is a fundamental aspect of metastasis. A detailed understanding of...
2.
Kula A, Makuch E, Lisowska M, Reniewicz P, Lipinski T, Siednienko J
Immunology
. 2023 Mar;
169(3):369-383.
PMID: 36861386
Viral infection activates the innate immune system, which recognizes viral components by a variety of pattern recognition receptors and initiates signalling cascades leading to the production of pro-inflammatory cytokines. To...
3.
Kazana W, Jakubczyk D, Siednienko J, Zambrowicz A, Macala J, Zablocka A
Mol Neurobiol
. 2023 Feb;
60(5):2819-2831.
PMID: 36735179
Food-derived bioactive peptides able to regulate neuronal function have been intensively searched and studied for their potential therapeutic application. Our previous study showed that a polypeptide complex yolkin, isolated from...
4.
Makuch E, Jasyk I, Kula A, Lipinski T, Siednienko J
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499241
IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced...
5.
Kazana W, Jakubczyk D, Pacyga-Prus K, Leszczynska K, Gorska S, Siednienko J, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328547
Ageing is accompanied by the inevitable changes in the function of the immune system. It provides increased susceptibility to chronic infections that have a negative impact on the quality of...
6.
Reniewicz P, Kula A, Makuch E, Ochnik M, Lipinski T, Siednienko J
Oxid Med Cell Longev
. 2021 Jul;
2021:6668463.
PMID: 34306313
Sensing of viral particles and elements that initiate mechanisms of immune response is an intrinsic ability of mammalian cells. Regulatory cytokines and antiviral mediators are released after triggering of complex...
7.
Leszczynska E, Makuch E, Mitkiewicz M, Jasyk I, Narita M, Gorska S, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33255528
Activation of TLR7 by small imidazoquinoline molecules such as R848 or R837 initiates signaling cascades leading to the activation of transcription factors, such as AP-1, NF-κB, and interferon regulatory factors...
8.
Zyzak J, Mitkiewicz M, Leszczynska E, Reniewicz P, Moynagh P, Siednienko J
J Innate Immun
. 2019 Dec;
12(5):387-398.
PMID: 31851971
Innate immune response is a universal mechanism against invading pathogens. Toll-like receptors (TLRs), being part of a first line of defense, are responsible for detecting a variety of microorganisms. Among...
9.
Mitkiewicz M, Bac B, Kuropatwa M, Kurowska E, Matuszyk J, Siednienko J
Acta Biochim Pol
. 2018 Jul;
65(3):409-414.
PMID: 29959857
Cyclic guanosine monophosphate (cGMP) is synthesized by two types of enzymes: particulate (membrane-bound) guanylyl cyclases (pGCs) and soluble (cytosolic) guanylyl cyclases (sGCs). sGCs are primarily activated by binding of nitric...
10.
Gupta S, Maratha A, Siednienko J, Natarajan A, Gajanayake T, Hoashi S, et al.
Sci Rep
. 2018 Apr;
8(1):5768.
PMID: 29622775
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.