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Sinead M Miggin

Explore the profile of Sinead M Miggin including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 468
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Miggin S, Lawler O, Kinsella B
J Biol Chem . 2016 Sep; 291(37):19259. PMID: 27613955
No abstract available.
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Connolly M, Rooney P, McGarry T, Maratha A, McCormick J, Miggin S, et al.
Ann Rheum Dis . 2015 Aug; 75(7):1392-8. PMID: 26290589
Introduction: Acute-phase serum amyloid A (A-SAA) has cytokine-like properties and is expressed at sites of inflammation. We examined whether A-SAA-induced pro-inflammatory mechanisms are mediated through Toll-like receptor 2 (TLR2) in...
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Shevlin E, Miggin S
PLoS One . 2014 Sep; 9(9):e107141. PMID: 25211222
Toll-like receptor 7 (TLR7) plays a vital role in the immune response to ssRNA viruses such as human rhinovirus (HRV) and Influenza, against which there are currently no treatments or...
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Butt A, Miggin S
J Biol Chem . 2014 Apr; PMID: 24719322
The manuscript was withdrawn by the author.
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Ahmed S, Maratha A, Butt A, Shevlin E, Miggin S
J Immunol . 2013 Feb; 190(5):2217-28. PMID: 23365087
TLRs are a group of pattern-recognition receptors that play a crucial role in danger recognition and induction of the innate immune response against bacterial and viral infections. The TLR adaptor...
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Butt A, Ahmed S, Maratha A, Miggin S
J Biol Chem . 2012 Sep; 287(46):38665-79. PMID: 22984265
Toll-like receptors (TLRs) are a group of pattern recognition receptors that play a crucial role in the induction of the innate immune response against bacterial and viral infections. TLR3 has...
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Butt A, Miggin S
Proteomics . 2012 May; 12(13):2127-38. PMID: 22623378
Oncovirus, synonymously called a 'tumour virus', is a virus that can cause cancer. An oncolytic virus preferentially infects the host's cancer cells and lyses them, causing tumour destruction, and is...
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Siednienko J, Maratha A, Yang S, Mitkiewicz M, Miggin S, Moynagh P
J Biol Chem . 2011 Nov; 286(52):44750-63. PMID: 22065573
The induction of β-interferon (IFN-β) is a key anti-viral response to infection by RNA viruses. Virus-induced expression of IFN-β requires the co-operative action of the transcription factors IRF-3/7, NF-κB, and...