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Sindhu Nair

Explore the profile of Sindhu Nair including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 170
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Recent Articles
1.
Ahmed S, K V, Kannoth S, Raeesa F, Misri Z, Mascarenhas D, et al.
Ann Neurosci . 2024 Nov; :09727531241230213. PMID: 39544637
Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an immune-mediated inflammatory disease of the central nervous system, the clinical phenotype of which includes meningoencephalitis, myelitis, optic neuritis, seizures, movement disorders,...
2.
White 2nd Z, Nair S, Bredel M
J Mol Med (Berl) . 2024 Apr; 102(6):751-760. PMID: 38639785
Annexins, a group of Ca-dependent phospholipid-binding proteins, exert diverse roles in neuronal development, normal central nervous system (CNS) functioning, neurological disorders, and CNS tumors. This paper reviews the roles of...
3.
Cui T, Corrales-Guerrero S, Castro-Aceituno V, Nair S, Maneval D, Monnig C, et al.
Mol Ther Oncolytics . 2023 Sep; 30:181-192. PMID: 37674628
Albumin is an attractive candidate carrier for the development of novel therapeutic drugs. Gemcitabine has been FDA approved for the treatment of solid tumors; however, new drugs that optimize gemcitabine...
4.
Corrales-Guerrero S, Cui T, Castro-Aceituno V, Yang L, Nair S, Feng H, et al.
Cancer Lett . 2023 Jul; 570:216308. PMID: 37482342
Glioblastoma (GBM) is an aggressive malignant primary brain tumor. Radioresistance largely contributes to poor clinical outcomes in GBM patients. We targeted ribonucleotide reductase subunit 2 (RRM2) with triapine to radiosensitize...
5.
Bredel M, Espinosa L, Kim H, Scholtens D, McElroy J, Rajbhandari R, et al.
Cell Rep Med . 2023 Jun; 4(6):101082. PMID: 37343523
Genetic alterations help predict the clinical behavior of diffuse gliomas, but some variability remains uncorrelated. Here, we demonstrate that haploinsufficient deletions of chromatin-bound tumor suppressor NFKB inhibitor alpha (NFKBIA) display...
6.
Ranganathan P, Tandon S, Khan S, Sharma P, Sharma S, Mishra G, et al.
J Cancer Policy . 2023 Feb; 36:100412. PMID: 36805892
Aim: Healthcare workers (HCWs) have reported negative social experiences during the COVID-19 pandemic; however, this data is largely from medical personnel. We examined living conditions, social determinants, and experiences during...
7.
Nair S, El-Yazbi A
Int J Biol Macromol . 2023 Feb; 233:123510. PMID: 36739048
Human genome is continuously susceptible to changes that may lead to undesirable mutations causing various diseases and cancer. Vast majority of techniques has investigated the discrimination between base-pair mismatched nucleic...
8.
Bhargavan R, Chandramohan K, Mathew A, Nair S
Indian J Surg Oncol . 2022 Sep; 8(3):423-425. PMID: 36118404
Pneumocytoma is a rare benign neoplasm which was described over 50 years ago. Over the years its nomenclature and histogenesis has been a subject of much debate and controversy. We...
9.
Sun K, Xu Y, Zhang L, Niravath P, Darcourt J, Patel T, et al.
Clin Cancer Res . 2022 Jul; 28(20):4392-4401. PMID: 35877117
Purpose: A Phase 2 trial of stereotactic radiotherapy and in situ cytotoxic virus therapy in patients with metastatic triple-negative breast cancer (mTNBC) followed by pembrolizumab (STOMP) was designed to evaluate...
10.
Nair S, Hainer A, El-Yazbi A
Int J Biol Macromol . 2022 Jul; 215:657-664. PMID: 35777509
Light in the UVC spectral region damages both single-strand (ssDNA) and double-strand DNA (dsDNA), and contributes to the formation of mutagenic photoproducts. In-vivo studies show greater damage for ssDNA compared...