Simone Sidoli
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Explore the profile of Simone Sidoli including associated specialties, affiliations and a list of published articles.
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208
Citations
4167
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Recent Articles
11.
Zhebrun A, Ni J, Corveleyn L, Ghosh Roy S, Sidoli S, Gu S
Genetics
. 2024 Dec;
229(2).
PMID: 39661453
Nuclear RNAi in Caenorhabditis elegans induces a set of transgenerationally heritable marks of H3K9me3, H3K23me3, and H3K27me3 at the target genes. The function of H3K23me3 in the nuclear RNAi pathway...
12.
Liu Y, Hrit J, Chomiak A, Stransky S, Hoffman J, Tiedemann R, et al.
Mol Cell
. 2024 Dec;
85(2):394-412.e12.
PMID: 39631394
Mono-ubiquitination of lysine 18 on histone H3 (H3K18ub), catalyzed by UHRF1, is a DNMT1 docking site that facilitates replication-coupled DNA methylation maintenance. Its functions beyond this are unknown. Here, we...
13.
Wortzel I, Seo Y, Akano I, Shaashua L, Tobias G, Hebert J, et al.
Nat Cancer
. 2024 Dec;
5(12):1815-1833.
PMID: 39627554
Extracellular vesicles (EVs) transport biomolecules that mediate intercellular communication. We previously showed that EVs contain DNA (EV-DNA) representing the entire genome. However, the mechanism of genomic EV-DNA packaging and its...
14.
Zhebrun A, Ni J, Corveleyn L, Ghosh Roy S, Sidoli S, Gu S
bioRxiv
. 2024 Nov;
PMID: 39574755
Nuclear RNAi in induces a set of transgenerationally heritable marks of H3K9me3, H3K23me3, and H3K27me3 at the target genes. The function of H3K23me3 in the nuclear RNAi pathway is largely...
15.
Nakane K, Morisseau C, Dowker-Key P, Benitez G, Aguilan J, Nagai E, et al.
ACS Med Chem Lett
. 2024 Nov;
15(11):1891-1898.
PMID: 39563815
Soluble epoxide hydrolase (sEH) is a bifunctional enzyme involved in fatty acid metabolism and a promising drug target. We previously reported first-generation sEH proteolysis-targeting chimeras (PROTACs) with limited degradation potency...
16.
Fleming A, Knatko E, Li X, Zoch A, Heckhausen Z, Stransky S, et al.
Genes Dev
. 2024 Nov;
38(21-24):952-964.
PMID: 39562138
The link between DNA methylation and neurodevelopmental disorders is well established. However, how DNA methylation is fine-tuned-ensuring precise gene expression and developmental fidelity-remains poorly understood. PROSER1, a known TET2 interactor,...
17.
Hamilton A, Radaoui A, Tsang M, Martinez D, Conkrite K, Patel K, et al.
Cancer Cell
. 2024 Oct;
42(11):1970-1982.e7.
PMID: 39454577
Cancer immunotherapies produce remarkable results in B cell malignancies; however, optimal cell surface targets for many solid cancers remain elusive. Here, we present an integrative proteomic, transcriptomic, and epigenomic analysis...
18.
Rosen B, Li Q, Cho H, Liu D, Yang D, Graff S, et al.
Nat Commun
. 2024 Oct;
15(1):8966.
PMID: 39419994
Pluripotent stem cells have remarkable self-renewal capacity: the ability to proliferate indefinitely while maintaining the pluripotent identity essential for their ability to differentiate into almost any cell type in the...
19.
Vilicich F, Vettiatil D, Kattapong-Graber S, Nawsheen N, Patel N, Quezada A, et al.
bioRxiv
. 2024 Oct;
PMID: 39386730
During development, precursor cells are continuously and intimately interacting with their extracellular environment, which guides their ability to generate functional tissues and organs. Much is known about the development of...
20.
Tuleta I, Hanna A, Humeres C, Aguilan J, Sidoli S, Zhu F, et al.
Cardiovasc Res
. 2024 Oct;
120(16):2047-2063.
PMID: 39373248
Aims: Transforming growth factor (TGF)-β is up-regulated in the diabetic myocardium and may mediate fibroblast activation. We aimed at examining the role of TGF-β-induced fibroblast activation in the pathogenesis of...