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Simone Severini

Explore the profile of Simone Severini including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 518
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Recent Articles
1.
Temko D, Tomlinson I, Severini S, Schuster-Bockler B, Graham T
Nat Commun . 2020 Apr; 11(1):1959. PMID: 32313050
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Rocchetto A, Aaronson S, Severini S, Carvacho G, Poderini D, Agresti I, et al.
Sci Adv . 2019 Apr; 5(3):eaau1946. PMID: 30944851
The number of parameters describing a quantum state is well known to grow exponentially with the number of particles. This scaling limits our ability to characterize and simulate the evolution...
3.
Banerji C, Panamarova M, Pruller J, Figeac N, Hebaishi H, Fidanis E, et al.
Hum Mol Genet . 2018 Nov; 28(8):1244-1259. PMID: 30462217
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy, linked to epigenetic derepression of D4Z4 repeats on chromosome 4q, leading to ectopic DUX4 expression. FSHD patient myoblasts have defective myogenic...
4.
Temko D, Tomlinson I, Severini S, Schuster-Bockler B, Graham T
Nat Commun . 2018 May; 9(1):1857. PMID: 29748584
Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have...
5.
Ciliberto C, Herbster M, Ialongo A, Pontil M, Rocchetto A, Severini S, et al.
Proc Math Phys Eng Sci . 2018 Feb; 474(2209):20170551. PMID: 29434508
Recently, increased computational power and data availability, as well as algorithmic advances, have led machine learning (ML) techniques to impressive results in regression, classification, data generation and reinforcement learning tasks....
6.
Banerji C, Panamarova M, Hebaishi H, White R, Relaix F, Severini S, et al.
Nat Commun . 2017 Dec; 8(1):2152. PMID: 29255294
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy, linked to hypomethylation of D4Z4 repeats on chromosome 4q causing expression of the DUX4 transcription factor. However, DUX4 is difficult to...
7.
Vinci W, Markstrom K, Boixo S, Roy A, Spedalieri F, Warburton P, et al.
Sci Rep . 2017 Feb; 7:40651. PMID: 28139752
No abstract available.
8.
Burgarth D, Giovannetti V, Hogben L, Severini S, Young M
Nat Comput . 2015 Aug; 14(3):485-490. PMID: 26300713
We design logic circuits based on the notion of zero forcing on graphs; each gate of the circuits is a gadget in which zero forcing is performed. We show that...
9.
Teschendorff A, Banerji C, Severini S, Kuehn R, Sollich P
Sci Rep . 2015 Apr; 5:9646. PMID: 25919796
One of the key characteristics of cancer cells is an increased phenotypic plasticity, driven by underlying genetic and epigenetic perturbations. However, at a systems-level it is unclear how these perturbations...
10.
Banerji C, Severini S, Caldas C, Teschendorff A
PLoS Comput Biol . 2015 Mar; 11(3):e1004115. PMID: 25793737
The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic...