Andrew E Teschendorff
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Explore the profile of Andrew E Teschendorff including associated specialties, affiliations and a list of published articles.
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148
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12074
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Recent Articles
1.
Chang J, Lu J, Liu Q, Xiang T, Zhang S, Yi Y, et al.
Cancer Cell
. 2025 Mar;
43(3):380-397.e7.
PMID: 40068596
Cancer development involves the co-evolution of cancer cells and their surrounding microenvironment, yet the dynamics of this interaction within the physical architecture remains poorly understood. Here, we present a spatial...
2.
Li Z, Du Z, Huang D, Teschendorff A
Sci Rep
. 2025 Feb;
15(1):5048.
PMID: 39934290
Deep learning (DL) and explainable artificial intelligence (XAI) have emerged as powerful machine-learning tools to identify complex predictive data patterns in a spatial or temporal domain. Here, we consider the...
3.
Teschendorff A, Horvath S
Nat Rev Genet
. 2025 Jan;
PMID: 39806006
Over the past decade, epigenetic clocks have emerged as powerful machine learning tools, not only to estimate chronological and biological age but also to assess the efficacy of anti-ageing, cellular...
4.
Tong H, Guo X, Jacques M, Luo Q, Eynon N, Teschendorff A
Aging (Albany NY)
. 2025 Jan;
16(22):13452-13504.
PMID: 39760516
The ability to accurately quantify biological age could help monitor and control healthy aging. Epigenetic clocks have emerged as promising tools for estimating biological age, yet they have been developed...
5.
Das S, Karuri S, Chakraborty J, Basu B, Chandra A, Aravindan S, et al.
Eur J Med Res
. 2024 Nov;
29(1):548.
PMID: 39543766
No abstract available.
6.
Das S, Karuri S, Chakraborty J, Basu B, Chandra A, Aravindan S, et al.
Eur J Med Res
. 2024 Sep;
29(1):458.
PMID: 39261895
Background: DNA methylation showed notable potential to act as a diagnostic marker in many cancers. Many studies proposed DNA methylation biomarker in OSCC detection, while most of these studies are...
7.
Yang Z, Liu X, Xu H, Teschendorff A, Xu L, Li J, et al.
Commun Biol
. 2024 Jul;
7(1):824.
PMID: 38971948
The expression dysregulation of microRNAs (miRNA) has been widely reported during cancer development, however, the underling mechanism remains largely unanswered. In the present work, we performed a systematic integrative study...
8.
Teschendorff A
Biochem Soc Trans
. 2024 Jun;
52(3):1503-1514.
PMID: 38856037
Despite recent biotechnological breakthroughs, cancer risk prediction remains a formidable computational and experimental challenge. Addressing it is critical in order to improve prevention, early detection and survival rates. Here, I...
9.
Li W, Xia M, Zeng H, Lin H, Teschendorff A, Gao X, et al.
Clin Epigenetics
. 2024 May;
16(1):70.
PMID: 38802969
Background: Obesity is a global public health concern linked to chronic diseases such as cardiovascular disease and type 2 diabetes (T2D). Emerging evidence suggests that epigenetic modifications, particularly DNA methylation,...
10.
Zhu T, Tong H, Du Z, Beck S, Teschendorff A
Nat Commun
. 2024 May;
15(1):4211.
PMID: 38760334
The cumulative number of stem cell divisions in a tissue, known as mitotic age, is thought to be a major determinant of cancer-risk. Somatic mutational and DNA methylation (DNAm) clocks...