Peter S Zammit
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Explore the profile of Peter S Zammit including associated specialties, affiliations and a list of published articles.
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99
Citations
5633
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Recent Articles
1.
Hernandez-Camacho J, Vicente-Garcia C, Ardila-Garcia L, Padilla-Campos A, Lopez-Lluch G, Santos-Ocana C, et al.
J Cachexia Sarcopenia Muscle
. 2024 Oct;
15(6):2402-2416.
PMID: 39354863
Background: ADCK genes encode aarF domain-containing mitochondrial kinases involved in coenzyme Q (CoQ) biosynthesis and regulation. Haploinsufficiency of ADCK2 in humans leads to adult-onset physical incapacity with reduced mitochondrial CoQ...
2.
Engquist E, Greco A, Joosten L, van Engelen B, Banerji C, Zammit P
iScience
. 2024 Jun;
27(6):109947.
PMID: 38840844
The routine need for myonuclear turnover in skeletal muscle, together with more sporadic demands for hypertrophy and repair, are performed by resident muscle stem cells called satellite cells. Muscular dystrophies...
3.
Nguyen T, Limpens M, Bouhmidi S, Paprzycki L, Legrand A, Decleves A, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542301
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent inherited muscle disorders and is linked to the inappropriate expression of the DUX4 transcription factor in skeletal muscles. The deregulated...
4.
Meinhold M, Verbrugge S, Shi A, Schonfelder M, Becker L, Jaspers R, et al.
Cell Tissue Res
. 2024 Jan;
395(3):271-283.
PMID: 38183459
In skeletal muscle, the Hippo effector Yap promotes satellite cell, myoblast, and rhabdomyoblast proliferation but prevents myogenic differentiation into multinucleated muscle fibres. We previously noted that Yap drives expression of...
5.
Nguyen T, Paprzycki L, Legrand A, Decleves A, Heher P, Limpens M, et al.
Skelet Muscle
. 2023 Dec;
13(1):21.
PMID: 38104132
Background: Hypoxia is known to modify skeletal muscle biological functions and muscle regeneration. However, the mechanisms underlying the effects of hypoxia on human myoblast differentiation remain unclear. The hypoxic response...
6.
Engquist E, Greco A, Joosten L, van Engelen B, Zammit P, Banerji C
Hum Mol Genet
. 2023 Oct;
33(2):182-197.
PMID: 37856562
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy. FSHD is highly heterogeneous, with patients following a variety of clinical trajectories, complicating clinical trials. Skeletal muscle in FSHD undergoes fibrosis...
7.
Banerji C, Greco A, Joosten L, van Engelen B, Zammit P
Brain Commun
. 2023 Sep;
5(5):fcad221.
PMID: 37731904
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable skeletal myopathy. Clinical trials for FSHD are hindered by heterogeneous biomarkers poorly associated with clinical severity, requiring invasive muscle biopsy. Macroscopically, FSHD...
8.
Cowley M, Pruller J, Ganassi M, Zammit P, Banerji C
Elife
. 2023 May;
12.
PMID: 37184373
Facioscapulohumeral muscular dystrophy (FSHD) is an incurable myopathy linked to the over-expression of the myotoxic transcription factor DUX4. Targeting DUX4 is the leading therapeutic approach, however, it is only detectable...
9.
Ganassi M, Zammit P, Hughes S
Methods Mol Biol
. 2023 Mar;
2640:21-43.
PMID: 36995585
Adult skeletal musculature experiences continuous physical stress, and hence requires maintenance and repair to ensure its continued efficient functioning. The population of resident muscle stem cells (MuSCs), termed satellite cells,...
10.
Pinton L, Khedr M, Lionello V, Sarcar S, Maffioletti S, Dastidar S, et al.
Nat Protoc
. 2023 Feb;
18(4):1337-1376.
PMID: 36792780
Skeletal muscle is a complex tissue composed of multinucleated myofibers responsible for force generation that are supported by multiple cell types. Many severe and lethal disorders affect skeletal muscle; therefore,...