Simone C da Silva Rosa
Overview
Explore the profile of Simone C da Silva Rosa including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
316
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0
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Recent Articles
1.
Clark C, Behrooz A, da Silva Rosa S, Jacobs J, Weng X, Srivastava A, et al.
bioRxiv
. 2024 Sep;
PMID: 39253475
Temozolomide (TMZ) resistance in glioblastoma (GB) poses a significant therapeutic challenge. We developed a TMZ-resistant (TMZ-R) U251 GB model, revealing distinct differences in cell viability, apoptosis, autophagy, and lipid metabolism...
2.
Alizadeh J, da Silva Rosa S, Cordani M, Ghavami S
Methods Mol Biol
. 2024 Apr;
2879:261-273.
PMID: 38607594
Non-small cell lung cancer (NSCLC) is a predominant form of lung cancer characterized by its aggressive nature and high mortality rate, primarily due to late-stage diagnosis and metastatic spread. Recent...
3.
da Silva Rosa S, Behrooz A, Guedes S, Vitorino R, Ghavami S
Expert Rev Proteomics
. 2024 Apr;
21(4):125-147.
PMID: 38563427
Introduction: Gene identification for genetic diseases is critical for the development of new diagnostic approaches and personalized treatment options. Prioritization of gene translation is an important consideration in the molecular...
4.
Bhushan B, Iranpour R, Eshtiaghi A, da Silva Rosa S, Lindsey B, Gordon J, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474036
Alveolar rhabdomyosarcoma (ARMS), an invasive subtype of rhabdomyosarcoma (RMS), is associated with chromosomal translocation events resulting in one of two oncogenic fusion genes, or . ARMS patients exhibit an overexpression...
5.
da Silva Rosa S, Alizadeh J, Vitorino R, Surendran A, Ravandi A, Kidane B, et al.
Methods Mol Biol
. 2024 Mar;
2879:239-260.
PMID: 38441721
Non-small cell lung cancer (NSCLC) is among the most malignant tumors with high propensity for metastasis and is the leading cause of cancer-related death globally. Most patients present with regional...
6.
Jacobs J, Iranpour R, Behrooz A, da Silva Rosa S, Ghavami S
Biochem Cell Biol
. 2023 Nov;
102(2):127-134.
PMID: 37988705
Glioblastoma (GBM) is the most common aggressive central nervous system cancer. GBM has a high mortality rate, with a median survival time of 12-15 months after diagnosis. A poor prognosis...
7.
Alizadeh J, da Silva Rosa S, Weng X, Jacobs J, Lorzadeh S, Ravandi A, et al.
Eur J Cell Biol
. 2023 Jul;
102(3):151337.
PMID: 37392580
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context of cancer. These mechanisms of regulation, however, appear...
8.
Behrooz A, Latifi-Navid H, da Silva Rosa S, Swiat M, Wiechec E, Vitorino C, et al.
Cancers (Basel)
. 2023 Jun;
15(12).
PMID: 37370767
The most aggressive primary malignant brain tumor in adults is glioblastoma (GBM), which has poor overall survival (OS). There is a high relapse rate among patients with GBM despite maximally...
9.
Martelli A, Omrani M, Zarghooni M, Citi V, Brogi S, Calderone V, et al.
Cancers (Basel)
. 2022 Dec;
14(23).
PMID: 36497321
Macroautophagy (autophagy) has been a highly conserved process throughout evolution and allows cells to degrade aggregated/misfolded proteins, dysfunctional or superfluous organelles and damaged macromolecules, in order to recycle them for...
10.
Dalvand A, da Silva Rosa S, Ghavami S, Marzban H
Biochem Biophys Rep
. 2022 Oct;
32:101358.
PMID: 36213145
During development, the interconnected generation of various neural cell types within the cerebellar primordium is essential. Over embryonic (E) days E9-E13, Purkinje cells (PCs), and cerebellar nuclei (CN) neurons are...