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Joadi Jacobs

Explore the profile of Joadi Jacobs including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Clark C, Behrooz A, da Silva Rosa S, Jacobs J, Weng X, Srivastava A, et al.
bioRxiv . 2024 Sep; PMID: 39253475
Temozolomide (TMZ) resistance in glioblastoma (GB) poses a significant therapeutic challenge. We developed a TMZ-resistant (TMZ-R) U251 GB model, revealing distinct differences in cell viability, apoptosis, autophagy, and lipid metabolism...
2.
Jacobs J, Iranpour R, Behrooz A, da Silva Rosa S, Ghavami S
Biochem Cell Biol . 2023 Nov; 102(2):127-134. PMID: 37988705
Glioblastoma (GBM) is the most common aggressive central nervous system cancer. GBM has a high mortality rate, with a median survival time of 12-15 months after diagnosis. A poor prognosis...
3.
Alizadeh J, da Silva Rosa S, Weng X, Jacobs J, Lorzadeh S, Ravandi A, et al.
Eur J Cell Biol . 2023 Jul; 102(3):151337. PMID: 37392580
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context of cancer. These mechanisms of regulation, however, appear...