Simone C da Silva Rosa
Overview
Explore the profile of Simone C da Silva Rosa including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
316
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0
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Recent Articles
11.
da Silva Rosa S, Liu M, Sweeney G
Physiology (Bethesda)
. 2021 Apr;
36(3):134-149.
PMID: 33904786
Adiponectin, an adipokine that circulates as multiple multimeric complexes at high levels in serum, has antidiabetic, anti-inflammatory, antiatherogenic, and cardioprotective properties. Understanding the mechanisms regulating adiponectin's physiological effects is likely...
12.
da Silva Rosa S, Martens M, Field J, Nguyen L, Kereliuk S, Hai Y, et al.
Autophagy
. 2020 Oct;
17(9):2257-2272.
PMID: 33044904
Lipotoxicity is a form of cellular stress caused by the accumulation of lipids resulting in mitochondrial dysfunction and insulin resistance in muscle. Previously, we demonstrated that the mitophagy receptor BNIP3L/Nix...
13.
da Silva Rosa S, Nayak N, Caymo A, Gordon J
Physiol Rep
. 2020 Oct;
8(19):e14607.
PMID: 33038072
Insulin resistance is a metabolic disorder affecting multiple tissues and is a precursor event to type 2 diabetes (T2D). As T2D affects over 425 million people globally, there is an...
14.
Ahmadi M, Amiri S, Pecic S, Machaj F, Rosik J, Los M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2020 Sep;
1866(12):165968.
PMID: 32927022
The statin drugs ('statins') potently inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by competitively blocking the active site of the enzyme. Statins decrease de novo cholesterol biosynthesis and thereby reduce plasma cholesterol...
15.
Emami A, Shojaei S, da Silva Rosa S, Aghaei M, Samiei E, Vosoughi A, et al.
Eur J Pharmacol
. 2019 Aug;
862:172616.
PMID: 31449810
Statins are some of the most widely used drugs worldwide, but one of their major side effects is myotoxicity. Using mouse myoblast (C2C12) and human alveolar rhabdomyosarcoma cell lines (RH30)...
16.
Moghadam A, da Silva Rosa S, Samiei E, Alizadeh J, Field J, Kawalec P, et al.
Cell Death Discov
. 2018 Nov;
4:52.
PMID: 30416757
Rhabdomyosarcoma (RMS) is a muscle-derived tumor. In both pre-clinical and clinical studies Temozolomide (TMZ) has been recently tested against RMS; however, the precise mechanism of action of TMZ in RMS...