Simon Joubert
Overview
Explore the profile of Simon Joubert including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
158
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Recent Articles
1.
Delafosse L, Lord-Dufour S, Pelletier A, Perret S, Burlacu A, Ouimet M, et al.
Methods Mol Biol
. 2024 Jun;
2810:99-121.
PMID: 38926275
The continuous improvement of expression platforms is necessary to respond to the increasing demand for recombinant proteins that are required to carry out structural or functional studies as well as...
2.
Joubert S, Stuible M, Lord-Dufour S, Lamoureux L, Vaillancourt F, Perret S, et al.
Biotechnol Bioeng
. 2023 Mar;
120(7):1746-1761.
PMID: 36987713
Protein expression from stably transfected Chinese hamster ovary (CHO) clones is an established but time-consuming method for manufacturing therapeutic recombinant proteins. The use of faster, alternative approaches, such as non-clonal...
3.
Joubert S, Guimond J, Perret S, Malenfant F, Elahi S, Marcil A, et al.
Biotechnol Bioeng
. 2022 May;
119(8):2206-2220.
PMID: 35509261
Some effector functions prompted by immunoglobulin G (IgG) antibodies, such as antibody-dependent cell-mediated cytotoxicity (ADCC), strongly depend on the N-glycans linked to asparagine 297 of the Fc region of the...
4.
Joubert S, Dodelet V, Beliard R, Durocher Y
Med Sci (Paris)
. 2020 Jan;
35(12):1153-1159.
PMID: 31903930
Antibody-based drugs are an increasingly important part of the therapeutic arsenal against a wide variety of medical conditions. As the number of commercial products and pipeline candidates grows, a crucial...
5.
Ndong J, Makowski A, Uppuganti S, Vignaux G, Ono K, Perrien D, et al.
Nat Med
. 2015 Apr;
21(4):414.
PMID: 25849275
No abstract available.
6.
Ndong J, Makowski A, Uppuganti S, Vignaux G, Ono K, Perrien D, et al.
Nat Med
. 2014 Jul;
20(8):904-10.
PMID: 24997609
Individuals with neurofibromatosis type-1 (NF1) can manifest focal skeletal dysplasias that remain extremely difficult to treat. NF1 is caused by mutations in the NF1 gene, which encodes the RAS GTPase-activating...
7.
Gagnon D, Joubert S, Senechal H, Fradet-Turcotte A, Torre S, Archambault J
J Virol
. 2009 Feb;
83(9):4127-39.
PMID: 19211738
The E2 protein of human papillomavirus (HPV) binds to specific sites in the viral genome to regulate its transcription, replication, and maintenance in infected cells. Like most regulatory proteins, E2...
8.
Cote-Martin A, Moody C, Fradet-Turcotte A, DAbramo C, Lehoux M, Joubert S, et al.
J Virol
. 2007 Nov;
82(3):1271-83.
PMID: 18032488
Due to the limited coding capacity of their small genomes, human papillomaviruses (HPV) rely extensively on host factors for the completion of their life cycles. Accordingly, most HPV proteins, including...
9.
Fradet-Turcotte A, Vincent C, Joubert S, Bullock P, Archambault J
J Virol
. 2007 Jun;
81(17):9162-74.
PMID: 17596312
SV40 large T antigen (T-ag) is a multifunctional protein that successively binds to 5'-GAGGC-3' sequences in the viral origin of replication, melts the origin, unwinds DNA ahead of the replication...
10.
Joubert S, McNicoll N, De Lean A
Biochem Pharmacol
. 2007 Jan;
73(7):954-63.
PMID: 17196175
Guanylyl cyclases catalyze the formation of cGMP from GTP. This family of enzymes includes soluble (sGC) and particulate guanylyl cyclases (pGC). The sGC are heterodimers containing one active catalytic site...