Simon J North
Overview
Explore the profile of Simon J North including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
1245
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Abouelhadid S, Atkins E, Kay E, Passmore I, North S, Lehri B, et al.
Microb Cell Fact
. 2023 Aug;
22(1):159.
PMID: 37596672
Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine assembly and production...
2.
North S, Botchway K, Doonan J, Lumb F, Dell A, Harnett W, et al.
Glycobiology
. 2019 May;
29(8):562-571.
PMID: 31094418
ES-62 is the major secreted product of the parasitic filarial nematode Acanthocheilonema viteae and has potent anti-inflammatory activities as a consequence of posttranslational decoration by phosphorylcholine (PC). Previously, we showed...
3.
Abouelhadid S, North S, Hitchen P, Vohra P, Chintoan-Uta C, Stevens M, et al.
mBio
. 2019 Apr;
10(2).
PMID: 31015322
In eukaryotes, glycosylation plays a role in proteome stability, protein quality control, and modulating protein function; however, similar studies in bacteria are lacking. Here, we investigate the roles of general...
4.
Veerapen N, Sharma Kharkwal S, Jervis P, Bhowruth V, Besra A, North S, et al.
Bioconjug Chem
. 2018 Aug;
29(9):3161-3173.
PMID: 30085659
Activation of invariant natural killer T lymphocytes (iNKT cells) by α-galactosylceramide (α-GC) elicits a range of pro-inflammatory or anti-inflammatory immune responses. We report the synthesis and characterization of a series...
5.
Panico M, Bouche L, Binet D, OConnor M, Rahman D, Pang P, et al.
Sci Rep
. 2016 Sep;
6:32956.
PMID: 27604319
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120(SU) plays an essential role in virus binding to target CD4+ T-cells and is a major vaccine target....
6.
Wu G, Hitchen P, Panico M, North S, Barbouche M, Binet D, et al.
Glycoconj J
. 2015 Dec;
33(3):447-56.
PMID: 26687240
Glycans serve as important regulators of antibody activities and half-lives. IgE is the most heavily glycosylated antibody, but in comparison to other antibodies little is known about its glycan structure...
7.
Halder S, Cotmore S, Heimburg-Molinaro J, Smith D, Cummings R, Chen X, et al.
PLoS One
. 2014 Jan;
9(1):e86909.
PMID: 24475195
The recognition of sialic acids by two strains of minute virus of mice (MVM), MVMp (prototype) and MVMi (immunosuppressive), is an essential requirement for successful infection. To understand the potential...
8.
Antonopoulos A, North S, Haslam S, Dell A
Biochem Soc Trans
. 2011 Sep;
39(5):1334-40.
PMID: 21936811
N-glycans are key players mediating cell-cell communication in the immune system, interacting with glycan-binding proteins. In the present article, we discuss key themes that are emerging from the structural analysis...
9.
North S, von Gunten S, Antonopoulos A, Trollope A, Macglashan Jr D, Jang-Lee J, et al.
Glycobiology
. 2011 Jul;
22(1):12-22.
PMID: 21725073
In allergic diseases such as asthma, eosinophils, basophils and mast cells, through release of preformed and newly generated mediators, granule proteins and cytokines, are recognized as key effector cells. While...
10.
Barthel S, Antonopoulos A, Cedeno-Laurent F, Schaffer L, Hernandez G, Patil S, et al.
J Biol Chem
. 2011 Apr;
286(24):21717-31.
PMID: 21493714
Prior studies have shown that treatment with the peracetylated 4-fluorinated analog of glucosamine (4-F-GlcNAc) elicits anti-skin inflammatory activity by ablating N-acetyllactosamine (LacNAc), sialyl Lewis X (sLe(X)), and related lectin ligands...