Silvia A Fuertes Marraco
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Explore the profile of Silvia A Fuertes Marraco including associated specialties, affiliations and a list of published articles.
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27
Citations
1975
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Recent Articles
11.
Neubert N, Schmittnaegel M, Bordry N, Nassiri S, Wald N, Martignier C, et al.
Sci Transl Med
. 2018 Apr;
10(436).
PMID: 29643229
Colony-stimulating factor 1 (CSF1) is a key regulator of monocyte/macrophage differentiation that sustains the protumorigenic functions of tumor-associated macrophages (TAMs). We show that CSF1 is expressed in human melanoma, and...
12.
Bovay A, Zoete V, Dolton G, Bulek A, Cole D, Rizkallah P, et al.
Eur J Immunol
. 2017 Oct;
48(2):258-272.
PMID: 28975614
The repertoire of human αβ T-cell receptors (TCRs) is generated via somatic recombination of germline gene segments. Despite this enormous variation, certain epitopes can be immunodominant, associated with high frequencies...
13.
Neubert N, Tille L, Barras D, Soneson C, Baumgaertner P, Rimoldi D, et al.
Cancer Res
. 2017 Jan;
77(7):1623-1636.
PMID: 28104684
Although mutations drive cancer, it is less clear to what extent genetic defects control immune mechanisms and confer resistance to T-cell-based immunotherapy. Here, we studied the reactions of malignant and...
14.
Murray T, Fuertes Marraco S, Baumgaertner P, Bordry N, Cagnon L, Donda A, et al.
Front Immunol
. 2016 Dec;
7:573.
PMID: 28018343
A major limiting factor in the success of immunotherapy is tumor infiltration by CD8 T cells, a process that remains poorly understood. In the present study, we characterized homing receptors...
15.
Neubert N, Soneson C, Barras D, Baumgaertner P, Rimoldi D, Delorenzi M, et al.
Front Immunol
. 2016 Sep;
7:326.
PMID: 27625650
While T cell-based immunotherapies are steadily improving, there are still many patients who progress, despite T cell-infiltrated tumors. Emerging evidence suggests that T cells themselves may provoke immune escape of...
16.
Fuertes Marraco S, Soneson C, Delorenzi M, Speiser D
Genom Data
. 2015 Oct;
5:297-301.
PMID: 26484272
The live-attenuated Yellow Fever (YF) vaccine YF-17D induces a broad and polyfunctional CD8 T cell response in humans. Recently, we identified a population of stem cell-like memory CD8 T cells...
17.
Fuertes Marraco S, Neubert N, Verdeil G, Speiser D
Front Immunol
. 2015 Jul;
6:310.
PMID: 26167163
Inhibitory receptors (iRs) are frequently associated with "T cell exhaustion". However, the expression of iRs is also dependent on T cell differentiation and activation. Therapeutic blockade of various iRs, also...
18.
Verdeil G, Fuertes Marraco S, Murray T, Speiser D
Biochim Biophys Acta
. 2015 Jul;
1865(1):49-57.
PMID: 26123831
The immune system has the potential to protect from malignant diseases for extended periods of time. Unfortunately, spontaneous immune responses are often inefficient. Significant effort is required to develop reliable,...
19.
Szeles L, Meissner F, Dunand-Sauthier I, Thelemann C, Hersch M, Singovski S, et al.
J Immunol
. 2015 Jun;
195(3):1025-33.
PMID: 26101320
Because of their unique capacity to cross-present Ags to CD8(+) T cells, mouse lymphoid tissue-resident CD8(+) dendritic cells (DCs) and their migratory counterparts are critical for priming antiviral T cell...
20.
Fuertes Marraco S, Soneson C, Cagnon L, Gannon P, Allard M, Maillard S, et al.
Sci Transl Med
. 2015 Apr;
7(282):282ra48.
PMID: 25855494
Efficient and persisting immune memory is essential for long-term protection from infectious and malignant diseases. The yellow fever (YF) vaccine is a live attenuated virus that mediates lifelong protection, with...