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Silke B Chalmers

Explore the profile of Silke B Chalmers including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 142
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Recent Articles
1.
Folacci M, Chalmers S, Davis F
Methods Mol Biol . 2024 Oct; 2861:195-212. PMID: 39395107
The mammary gland has a central role in optimal mammalian development and survival. Contractions of smooth muscle-like basal (or myoepithelial) cells in the functionally mature mammary gland in response to...
2.
Janke E, Chalmers S, Roberts-Thomson S, Monteith G
Cell Calcium . 2023 Apr; 112:102741. PMID: 37060674
Epithelial-mesenchymal transition (EMT) is a form of cellular phenotypic plasticity and is considered a crucial step in the progression of many cancers. The calcium ion (Ca) acts as a ubiquitous...
3.
Diercks B, Jensen H, Chalmers S, Coode E, Vaughan M, Tadayon R, et al.
Biochim Biophys Acta Mol Cell Res . 2021 Mar; 1868(6):118999. PMID: 33711364
The first junior European Calcium Society online meeting, held October 20-21, 2020, aimed to promote junior researchers in the Ca community. The meeting included four scientific sessions, covering Ca research...
4.
Azimi I, Stevenson R, Zhang X, Meizoso-Huesca A, Xin P, Johnson M, et al.
ACS Pharmacol Transl Sci . 2020 Mar; 3(1):135-147. PMID: 32190822
Store operated calcium (Ca) entry is an important homeostatic mechanism in cells, whereby the release of Ca from intracellular endoplasmic reticulum stores triggers the activation of a Ca influx pathway....
5.
Stewart T, Azimi I, Marcial D, Peters A, Chalmers S, Yapa K, et al.
Lab Invest . 2019 Jun; 100(2):224-233. PMID: 31243341
The Ca signal is essential in both hypoxia- and epidermal growth factor (EGF)-mediated epithelial to mesenchymal transition (EMT) in MDA-MB-468 breast cancer cells. This finding suggests that Ca-permeable ion channels...
6.
Roberts-Thomson S, Chalmers S, Monteith G
Cold Spring Harb Perspect Biol . 2019 May; 11(8). PMID: 31088826
Processes that are important in cancer progression, such as sustained cell growth, invasion to other organs, and resistance to cell death inducers, have a clear overlap with pathways regulated by...
7.
Azimi I, Milevskiy M, Chalmers S, Yapa K, Robitaille M, Henry C, et al.
Cancers (Basel) . 2019 Feb; 11(2). PMID: 30754719
The remodeling of specific calcium-permeable ion channels is a feature of some breast cancer subtypes. ORAI1 is a protein that forms a calcium-permeable ion channel responsible for store-operated calcium entry...
8.
Chalmers S, Monteith G
Cell Calcium . 2018 Aug; 74:160-167. PMID: 30086406
Cancer is a major cause of death. The diversity of cancer types and the propensity of cancers to acquire resistance to therapies, including new molecularly targeted and immune-based therapies, drives...