Bjorn-Philipp Diercks
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Explore the profile of Bjorn-Philipp Diercks including associated specialties, affiliations and a list of published articles.
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32
Citations
332
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Recent Articles
1.
Asada N, Ginsberg P, Paust H, Song N, Riedel J, Turner J, et al.
Nat Immunol
. 2025 Mar;
PMID: 40050432
Tissue-resident memory T (T) cells are a specialized T cell population that reside in tissues and provide a rapid protective response upon activation. Here, we showed that human and mouse...
2.
Gerlach F, Mockl F, Kovacevic D, Brock V, Winzer R, Meyer L, et al.
J Vis Exp
. 2024 Oct;
(212).
PMID: 39431792
Local, sub-second Ca signals, termed Ca microdomains, are highly dynamic and short-lived Ca signals, which result in a global [Ca]i elevation and might already determine the fate of a T...
3.
Bultynck G, Diercks B, Kallay E, Mackrill J
Biochim Biophys Acta Mol Cell Res
. 2024 Oct;
1872(3):119861.
PMID: 39393472
No abstract available.
4.
Krukenberg S, Mockl F, Weiss M, Dekiert P, Hofmann M, Gerlach F, et al.
Nat Commun
. 2024 Sep;
15(1):8008.
PMID: 39271671
Upon stimulation of membrane receptors, nicotinic acid adenine dinucleotide phosphate (NAADP) is formed as second messenger within seconds and evokes Ca signaling in many different cell types. Here, to directly...
5.
Ornelas-Guevara R, Diercks B, Guse A, Dupont G
Biochim Biophys Acta Mol Cell Res
. 2024 Aug;
1871(8):119808.
PMID: 39151474
Ca signalling is pivotal in T cell activation, an essential process in adaptive immune responses. Key to this activation are Ca microdomains, which are transient increases in cytosolic Ca concentration...
6.
Diercks B
Biochim Biophys Acta Mol Cell Res
. 2024 Mar;
1871(5):119710.
PMID: 38522726
Calcium signaling stands out as the most widespread and universally used signaling system and is of utmost importance for immunity. Controlled elevations in cytosolic and organellar Ca concentrations in T...
7.
Brock V, Lory N, Mockl F, Birus M, Stahler T, Woelk L, et al.
Front Immunol
. 2024 Mar;
15:1258119.
PMID: 38426095
CD8 T cells are a crucial part of the adaptive immune system, responsible for combating intracellular pathogens and tumor cells. The initial activation of T cells involves the formation of...
8.
Woelk L, Kovacevic D, Husseini H, Forster F, Gerlach F, Mockl F, et al.
Front Immunol
. 2024 Jan;
14:1299435.
PMID: 38274810
Ca microdomains play a key role in intracellular signaling processes. For instance, they mediate the activation of T cells and, thus, the initial adaptive immune system. They are, however, also...
9.
Gil Montoya D, Ornelas-Guevara R, Diercks B, Guse A, Dupont G
Front Immunol
. 2023 Oct;
14:1235737.
PMID: 37860008
Cellular Ca signaling is highly organized in time and space. Locally restricted and short-lived regions of Ca increase, called Ca microdomains, constitute building blocks that are differentially arranged to create...
10.
Weiss M, Hernandez L, Gil Montoya D, Lohndorf A, Kruger A, Kopdag M, et al.
Sci Signal
. 2023 Jun;
16(790):eabn9405.
PMID: 37339181
During an immune response, T cells migrate from blood vessel walls into inflamed tissues by migrating across the endothelium and through extracellular matrix (ECM). Integrins facilitate T cell binding to...