Sihan Wu
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Explore the profile of Sihan Wu including associated specialties, affiliations and a list of published articles.
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64
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1759
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Recent Articles
1.
Lv W, Zeng Y, Li C, Liang Y, Tao H, Zhu Y, et al.
Cancer Discov
. 2025 Mar;
PMID: 40062518
Extrachromosomal DNA (ecDNA) presents a promising target for cancer therapy; however, its spatial-temporal diversity and influence on tumor evolution and the immune microenvironment remain largely unclear. We apply computational methods...
2.
Tiwari A, Paithane U, Friedlein J, Tashiro K, Saulnier O, Barbosa K, et al.
bioRxiv
. 2025 Mar;
PMID: 40027648
MYC-driven (MYC+) cancers are aggressive and often fatal. MYC dysregulation is a key event in these cancers, but overexpression of MYC alone is not always enough to cause cancer. (),...
3.
Chen L, Li Z, Wang P, Wu S, Li W, Wang J, et al.
Nanomaterials (Basel)
. 2025 Feb;
15(3).
PMID: 39940166
Miniaturized pixel sizes in near-eye digital displays lead to pixel emission patterns with large divergence angles, necessitating efficient beam collimation solutions to improve the light coupling efficiency. Traditional beam collimation...
4.
Hung I, Yiu Y, Wu S, Liu D, Wang L, Han X
Sci Rep
. 2025 Jan;
15(1):3710.
PMID: 39881201
Civic honesty is a crucial behavior that policymakers and business leaders strive to promote among citizens and employees. We conducted online and field experiments in China adapting the setting of...
5.
Liu H, Zhang C, Peng S, Yin Y, Xu Y, Wu S, et al.
J Transl Med
. 2025 Jan;
23(1):127.
PMID: 39875913
Background: Tumor microenvironment (TME), particularly immune cell infiltration, programmed cell death (PCD) and stress, has increasingly become a focal point in colorectal cancer (CRC) treatment. Uncovering the intricate crosstalk between...
6.
Yang Q, Xie Y, Qiao K, Lim J, Wu S
Cell Res
. 2025 Jan;
35(1):11-22.
PMID: 39748050
Genomic instability is a hallmark of cancer and is a major driving force of tumorigenesis. A key manifestation of genomic instability is the formation of extrachromosomal DNAs (ecDNAs) - acentric,...
7.
Lou Q, Wu S, Zhang J, Xie R, Wu X, Guo Z, et al.
Int J Environ Health Res
. 2024 Sep;
:1-10.
PMID: 39225389
To explore whether rs2073244 at PAX9 increased susceptibility for full-term low birth weight infants and whether indoors passive smoking exposure has a combined effect with rs2073244 on newborn low birth...
8.
Tan Y, Lai T, Li Y, Tang Q, Zhang W, Liu Q, et al.
J Control Release
. 2024 Aug;
374:505-524.
PMID: 39182693
The secondary injuries following traumatic spinal cord injury (SCI) is a multiphasic and complex process that is difficult to treat. Although methylprednisolone (MP) is the only available pharmacological regime for...
9.
Xiao M, Ma D, Wu S, Huang Z, Liang P, Chen H, et al.
Hepatology
. 2024 Aug;
PMID: 39178365
Background And Aims: Biliary atresia (BA) is a devastating fibroinflammatory biliary disease that is the leading indication for pediatric liver transplants worldwide. Although cholangiocytes are the primary target cells, the...
10.
Gilbreath C, Peng Y, Wu S
J Vis Exp
. 2024 Jul;
(209).
PMID: 39072619
Focal gene amplification, such as extrachromosomal DNA (ecDNA), plays an important role in cancer development and therapy resistance. While sequencing-based methodologies enable an unbiased identification of ecDNA, cytogenetic-based techniques, such...