Sibylle Madlener
Overview
Explore the profile of Sibylle Madlener including associated specialties, affiliations and a list of published articles.
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55
Citations
1159
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Recent Articles
1.
Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, et al.
Cancer Cell
. 2025 Mar;
PMID: 40086436
PDGFRA is crucial to tumorigenesis and frequently genomically altered in high-grade glioma (HGG). In a comprehensive dataset of pediatric HGG (n = 261), we detect PDGFRA mutations and/or amplifications in...
2.
Madlener S, Stepien N, Senfter D, Mayr L, Laemmerer A, Hedrich C, et al.
Acta Neuropathol
. 2025 Jan;
149(1):5.
PMID: 39751690
Gliomas are the most common brain tumor type in children and adolescents. To date, diagnosis and therapy monitoring for these tumors rely on magnetic resonance imaging (MRI) and histopathological as...
3.
Laemmerer A, Lehmann C, Mayr L, Bruckner K, Gabler L, Senfter D, et al.
Neuro Oncol
. 2024 Nov;
27(3):811-827.
PMID: 39556024
Background: Diffuse hemispheric glioma, H3 G34R/V-mutant (DHG-H3G34) is characterized by poor prognosis and lack of effective treatment options. DHG-H3G34R further harbor deactivation of alpha-thalassemia/mental retardation syndrome X-linked protein (ATRX; DHG-H3G34R_ATRX)...
4.
Pokorna P, Palova H, Adamcova S, Jugas R, Al Tukmachi D, Kyr M, et al.
Lab Invest
. 2024 Oct;
104(12):102161.
PMID: 39442669
Despite significant improvement in the survival of pediatric patients with cancer, treatment outcomes for high-risk, relapsed, and refractory cancers remain unsatisfactory. Moreover, prolonged survival is frequently associated with long-term adverse...
5.
Liu I, Cruzeiro G, Bjerke L, Rogers R, Grabovska Y, Beck A, et al.
Cancer Cell
. 2024 Sep;
PMID: 39232581
Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are lethal brain tumors lacking targeted therapies. They originate from interneuronal precursors; however, leveraging this origin for therapeutic insights remains unexplored. Here, we delineate a...
6.
Mayr L, Steinmaurer T, Weseslindtner L, Madlener S, Strassl R, Gojo J, et al.
Pediatr Blood Cancer
. 2023 May;
:e30450.
PMID: 37246492
No abstract available.
7.
Stepien N, Senfter D, Furtner J, Haberler C, Dorfer C, Czech T, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37173990
Background: Liquid biopsy diagnostic methods are an emerging complementary tool to imaging and pathology techniques across various cancer types. However, there is still no established method for the detection of...
8.
Madlener S, Furtner J, Stepien N, Senfter D, Mayr L, Zeyda M, et al.
Acta Neuropathol
. 2023 Apr;
145(6):843-846.
PMID: 37020088
No abstract available.
9.
Mayr L, Steinmaurer T, Weseslindtner L, Madlener S, Strassl R, Gojo J, et al.
Pediatr Blood Cancer
. 2023 Jan;
70(5):e30220.
PMID: 36694406
No abstract available.
10.
Liu I, Jiang L, Samuelsson E, Marco Salas S, Beck A, Hack O, et al.
Nat Genet
. 2022 Dec;
54(12):1881-1894.
PMID: 36471067
Histone 3 lysine27-to-methionine (H3-K27M) mutations most frequently occur in diffuse midline gliomas (DMGs) of the childhood pons but are also increasingly recognized in adults. Their potential heterogeneity at different ages...