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Sibylle Groeters

Explore the profile of Sibylle Groeters including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 54
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Recent Articles
1.
Thoma T, Ma-Hock L, Schneider S, Honarvar N, Treumann S, Groeters S, et al.
Part Fibre Toxicol . 2024 May; 21(1):24. PMID: 38760761
Background: Significant variations exist in the forms of ZnO, making it impossible to test all forms in in vivo inhalation studies. Hence, grouping and read-across is a common approach under...
2.
Landsiedel R, Hahn D, Ossig R, Ritz S, Sauer L, Buesen R, et al.
Part Fibre Toxicol . 2022 Mar; 19(1):21. PMID: 35321750
Background: The oral uptake of nanoparticles is an important route of human exposure and requires solid models for hazard assessment. While the systemic availability is generally low, ingestion may not...
3.
Gauthier B, Bach U, Chanut F, Jonghe S, Groeters S, Mueller G, et al.
Toxicol Pathol . 2021 Aug; 50(1):147-152. PMID: 34433323
Many pharmaceutical companies have recently elected to stop maintaining good laboratory practices (GLP) status of their R&D sites. Similar discussions have also been engaged in the (agro)chemical industry. This opinion...
4.
Belcher S, Cline J, Conley J, Groeters S, Jefferson W, Law M, et al.
Toxicol Pathol . 2019 Dec; 47(8):1049-1071. PMID: 31833458
During the past 20 years, investigations involving endocrine active substances (EAS) and reproductive toxicity have dominated the landscape of ecotoxicological research. This has occurred in concert with heightened awareness in...
5.
Dagli M, Pandiri A, Wolf J, Groeters S, Haschek-Hock W
Toxicol Pathol . 2019 Sep; 47(8):1088-1095. PMID: 31554482
A wide range of career options is available globally in the environmental toxicologic pathology (ETP) arena including academia, government, contract research organizations, and the agrichemical/chemical industry. This small and specialized...
6.
Wiemann C, Goettel M, Vardy A, Elcombe B, Elcombe C, Chatham L, et al.
Toxicology . 2019 Aug; 426:152282. PMID: 31465819
In a 2-year study the herbicide metazachlor (BAS 479H) was shown to significantly increase the incidence of liver tumours in female Wistar rats at a dietary level of 8000 ppm....
7.
Molina R, Konduru N, Queiroz P, Figueroa B, Fu D, Ma-Hock L, et al.
Sci Rep . 2019 Jun; 9(1):8163. PMID: 31160608
We have shown that barium [from BaSO nanoparticles (NPs)] was cleared from the lungs faster than other poorly soluble NPs and translocated mostly to bone. We now studied barium biokinetics...
8.
Melching-Kollmuss S, Fussell K, Schneider S, Buesen R, Groeters S, Strauss V, et al.
Arch Toxicol . 2016 Feb; 91(1):143-162. PMID: 26914364
Prochloraz is an imidazole fungicide, and its regulatory toxicological data package has been primarily generated in the 1990s. More recently, studies have been published demonstrating an interaction with hormone receptors/steroidogenesis...
9.
Fussell K, Schneider S, Buesen R, Groeters S, Strauss V, Melching-Kollmuss S, et al.
Arch Toxicol . 2015 Nov; 89(12):2385-402. PMID: 26525394
The current investigation examines whether the model anti-androgenic substance flutamide is capable of disrupting endocrine homeostasis at very low doses. The data generated clarify whether a non-monotonic dose-response relationship exists...
10.
Strauss V, Kolle S, Honarvar N, Dammann M, Groeters S, Faulhammer F, et al.
J Appl Toxicol . 2014 Sep; 35(4):434-45. PMID: 25186098
The local lymph node assay (LLNA) is a regulatory accepted test for the identification of skin sensitizing substances by measuring radioactive thymidine incorporation into the lymph node. However, there is...