Shun-ichi Harada
Overview
Explore the profile of Shun-ichi Harada including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
907
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Recent Articles
1.
Schmidt A, Kimmel D, Bai C, Scafonas A, Rutledge S, Vogel R, et al.
J Biol Chem
. 2010 Apr;
285(22):17054-64.
PMID: 20356837
Selective androgen receptor modulators (SARMs) are androgen receptor (AR) ligands that induce anabolism while having reduced effects in reproductive tissues. In various experimental contexts SARMs fully activate, partially activate, or...
2.
Schmidt A, Harada S, Kimmel D, Bai C, Chen F, Rutledge S, et al.
J Biol Chem
. 2009 Oct;
284(52):36367-36376.
PMID: 19846549
Androgen replacement therapy is a promising strategy for the treatment of frailty; however, androgens pose risks for unwanted effects including virilization and hypertrophy of reproductive organs. Selective Androgen Receptor Modulators...
3.
OBryan M, Takada S, Kennedy C, Scott G, Harada S, Ray M, et al.
Dev Biol
. 2008 Mar;
316(2):359-70.
PMID: 18342849
Sox8 encodes a high-mobility group transcription factor that is widely expressed during development. Sox8, -9 and -10 form group E of the Sox gene family which has been implicated in...
4.
Nantermet P, Harada S, Liu Y, Cheng S, Johnson C, Yu Y, et al.
Endocrinology
. 2008 Jan;
149(4):1551-61.
PMID: 18187556
Androgens increase muscle mass, decrease fat mass, and reduce high-density lipoprotein cholesterol (HDL), but the relationship between body composition, lipoprotein metabolism, and androgens has not been explained. Here we treated...
5.
Kitagawa H, Ray W, Glantschnig H, Nantermet P, Yu Y, Leu C, et al.
Mol Cell Biol
. 2007 Aug;
27(21):7486-96.
PMID: 17709391
The orphan nuclear receptor Nurr1 is essential for the development and maintenance of midbrain dopaminergic neurons, the cells that degenerate during Parkinson's disease, by promoting the transcription of genes involved...
6.
Katagiri M, Ogasawara T, Hoshi K, Chikazu D, Kimoto A, Noguchi M, et al.
J Bone Miner Res
. 2006 Jan;
21(2):219-27.
PMID: 16418777
Unlabelled: In vitro assays revealed that COX-2 inhibitors with CA II inhibitory potency suppressed both differentiation and activity of osteoclasts, whereas that without the potency reduced only osteoclast differentiation. However,...
7.
Chen F, Knecht K, Birzin E, Fisher J, Wilkinson H, Mojena M, et al.
Endocrinology
. 2005 Jul;
146(11):4568-76.
PMID: 15994348
Dehydroepiandrosterone (DHEA) exhibits peak adrenal secretion in the fetus at term and around age 30 yr in the adult. Levels then progressively decline, which is associated with decreased levels of...
8.
Nantermet P, Masarachia P, Gentile M, Pennypacker B, Xu J, Holder D, et al.
Endocrinology
. 2004 Oct;
146(2):564-78.
PMID: 15498879
The androgen receptor (AR) is expressed in the uterus; however, the role of AR in female reproductive physiology is poorly understood. Here we examined the effects of androgens on uterine...
9.
Powzaniuk M, McElwee-Witmer S, Vogel R, Hayami T, Rutledge S, Chen F, et al.
Mol Endocrinol
. 2004 May;
18(8):2011-23.
PMID: 15131260
The androgen receptor (AR) is a member of the steroid receptor superfamily that plays critical roles in the development and maintenance of the male reproductive system and in prostate cancer....
10.
Wiren K, Zhang X, Toombs A, Kasparcova V, Gentile M, Harada S, et al.
Endocrinology
. 2004 May;
145(7):3507-22.
PMID: 15131013
The androgen receptor (AR), as a classic steroid receptor, generally mediates biologic responses to androgens. In bone tissue, both AR and the estrogen receptor (ER) are expressed in a variety...