Shridhar Narayanan
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Explore the profile of Shridhar Narayanan including associated specialties, affiliations and a list of published articles.
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59
Citations
678
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Recent Articles
11.
Mohankumar B, Shandil R, Narayanan S, Krishnan U
Microb Pathog
. 2022 Jun;
168:105606.
PMID: 35644292
Vaginosis is a condition experienced by most women at least once in their lifetime. This condition arises due to the imbalance in the microbiome of the vaginal ecosystem. Most of...
12.
Prabhu P, Fernandes T, Damani M, Chaubey P, Narayanan S, Sawarkar S
Curr Drug Deliv
. 2021 Dec;
19(8):830-845.
PMID: 34915835
Tuberculosis (TB) is an ancient chronic disease caused by the bacillus Mycobacterium tuberculosis, which has affected mankind for more than 4,000 years. Compliance with the standard conventional treatment can assure...
13.
Kaur P, Potluri V, Ahuja V, Naveenkumar C, Krishnamurthy R, Gangadharaiah S, et al.
Tuberculosis (Edinb)
. 2021 Jul;
129:102104.
PMID: 34214859
FNDR-20081 [4-{4-[5-(4-Isopropyl-phenyl)- [1,2,4]oxadiazol-3-ylmethyl]-piperazin-1-yl}-7-pyridin-3-yl-quinoline] is a novel, first in class anti-tubercular pre-clinical candidate against sensitive and drug-resistant Mycobacterium tuberculosis (Mtb). In-vitro combination studies of FNDR-20081 with first- and second-line drugs exhibited...
14.
Prabhu P, Fernandes T, Chaubey P, Kaur P, Narayanan S, Vk R, et al.
Drug Deliv Transl Res
. 2021 May;
11(4):1509-1519.
PMID: 34021478
Tuberculosis (TB) is a potentially fatal contagious disease and is a second leading infectious cause of death in the world. Osteoarticular TB is treated using standard regimen of 1st and...
15.
Narayanan S, Shandil R, Ahuja V, Shanmugam S, Mahesh K U H, Ramesh N, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2021 May;
1174:122714.
PMID: 33962189
Triciribine (TCN) is a tricyclic nucleoside analog of adenosine and an inhibitor of Akt kinase. Triciribine 5'-monophosphate (TCNP) is a water-soluble analog of Triciribine and has progressed to Phase I...
16.
Potluri V, Shandil R, Gavara R, Sambasivam G, Campo B, Wittlin S, et al.
Malar J
. 2020 Oct;
19(1):365.
PMID: 33046062
Background: Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for...
17.
Subramani P, Vartak-Sharma N, Sreekumar S, Mathur P, Nayer B, Dakhore S, et al.
Malar J
. 2020 Jun;
19(1):214.
PMID: 32571333
Background: Vivax malaria is associated with significant morbidity and economic loss, and constitutes the bulk of malaria cases in large parts of Asia and South America as well as recent...
18.
R M, Shandil R, Panda M, Sadler C, Ambady A, Panduga V, et al.
ACS Med Chem Lett
. 2019 Oct;
10(10):1480-1485.
PMID: 31620237
We report a novel benzimidazole (BI) based DprE1 inhibitor that resulted from scaffold morphing of a 1,4-azaindole series. The clinical progression of the 1,4-azaindole series from our previous work validates...
19.
Shruthi T, Eswaran S, Shivarudraiah P, Narayanan S, Subramanian S
Bioorg Med Chem Lett
. 2018 Nov;
29(1):97-102.
PMID: 30448235
Tuberculosis is the infectious disease caused by mycobacterium tuberculosis (Mtb), responsible for the utmost number of deaths annually across the world. Herein, twenty-one new substituted 1,2,4-oxadiazol-3-ylmethyl-piperazin-1-yl-quinoline derivatives were designed and...
20.
Nidhyanandan S, Thippeswamy B, Chandrasekhar K, Reddy N, Kulkarni N, Karthikeyan K, et al.
Anticancer Drugs
. 2017 Jul;
28(9):1002-1017.
PMID: 28727579
Vorinostat [suberoylanilide hydroxamic acid (SAHA)], a histone deacetylase inhibitor, shows limited clinical activity against solid tumors when used alone. The methyl xanthine drug, pentoxifylline (PENT), has been described to have...