Shoma Mikawa
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Explore the profile of Shoma Mikawa including associated specialties, affiliations and a list of published articles.
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11
Citations
48
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Recent Articles
1.
Mikawa S, Matsuda A, Kamemori Y, Asanuma S, Kitagawa H
Open Vet J
. 2021 Nov;
11(3):394-400.
PMID: 34722202
Background: Probiotics are known for their ability to enhance cellular immunity, including the activation of macrophages, natural killer (NK) cells, and cytotoxic T lymphocytes. Natto is a Japanese traditional probiotic...
2.
Mochizuki Y, Mikawa S, Kutara K, Sugimoto K, Sakoya H, Ohnishi A, et al.
Vet Sci
. 2021 Jul;
8(6).
PMID: 34201119
A 1-year-old female Akita dog was referred for intermittent regurgitation. Computed tomographic angiography (CTA) showed an aberrant right subclavian artery (ARSA), resulting in constriction of the esophagus. After surgical ligation...
3.
Aikiyo S, Kishi K, Kaji N, Mikawa S, Kondo M, Shimada S, et al.
Digestion
. 2020 Jul;
102(4):516-526.
PMID: 32726781
Introduction: The serotonin 3A receptor (5-HT3AR) is involved in vomiting and gastrointestinal motility. However, it is not well understood the expression pattern of 5-HT3AR in the gut immunohistochemically and how...
4.
Kimura H, Yoneya Y, Mikawa S, Kaji N, Ito H, Tsuchida Y, et al.
Biomed Pharmacother
. 2019 Dec;
123:109773.
PMID: 31862476
Zinc was discovered to be a novel second messenger in immunoreactive cells. We synthesized a novel free zinc chelator, IPZ-010. Here, we investigated the effects of IPZ-010 in a mouse...
5.
Mikawa S, Kondo M, Kaji N, Mihara T, Yoshitake R, Nakagawa T, et al.
FASEB J
. 2018 Sep;
33(2):1669-1680.
PMID: 30207796
Antagonists of the 5-hydroxytryptamine (serotonin) 3 receptor (5-HTR) have anti-inflammatory and anti-apoptotic activities, but the detailed, underlying mechanisms are not well understood. We focused on anti-apoptotic activities via 5-HTR signaling...
6.
Islam M, Kaji N, Mikawa S, Yang Q, Kusabe M, Hori M, et al.
J Vet Med Sci
. 2018 Apr;
80(6):977-984.
PMID: 29695674
Epithelial-mesenchymal transition (EMT) is an orchestral and functional change in epithelial cells. Many signaling pathways are involved in EMT, and transforming growth factor-beta (TGF-β) is considered to be one of...
7.
Mihara T, Otsubo W, Horiguchi K, Mikawa S, Kaji N, Iino S, et al.
J Vet Med Sci
. 2017 Sep;
79(11):1795-1802.
PMID: 28931778
Regulation of inflammation in intestinal mesothelial cells in the abdominal cavity is important for the pathogeny of clinical conditions, such as postoperative ileus, peritonitis and encapsulating peritoneal sclerosis. Here we...
8.
Mihara T, Mikawa S, Kaji N, Endo M, Oikawa T, Tong-Rong J, et al.
Inflammation
. 2017 May;
40(4):1331-1341.
PMID: 28493080
Postoperative ileus is a common complication after intra-abdominal surgery. Nitric oxide produced by macrophages in the inflamed gastrointestinal tract plays a crucial role in the pathogeny of postoperative ileus. Honokiol,...
9.
Mikawa S, Ohta Y, Kaji N, Islam M, Murata T, Ozaki H, et al.
J Vet Med Sci
. 2015 Jun;
77(11):1443-9.
PMID: 26051129
Endotoxin causes gastrointestinal motility disorder. Aim of this study is to clarify inhibitory mechanisms of lipopolysaccharide (LPS) on smooth muscle contraction in rat ileum. Ileal tissues were isolated from control...
10.
Mikawa S, Yamamoto S, Islam M, Kaji N, Murata T, Mizuno R, et al.
J Vet Med Sci
. 2015 May;
77(10):1195-9.
PMID: 25947563
Maropitant is a neurokinin 1 receptor (NK1R) antagonist that is clinically used as a new anti-emetic drug for dogs. Substance P (SP) and its receptor NK1R are considered to modulate...