Taiki Mihara
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Explore the profile of Taiki Mihara including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
51
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Recent Articles
1.
Mihara T, Tsuru Y, Kurosawa T, Nonoshita Y, Yamakawa Y, Hori M
Hepatol Commun
. 2025 Jan;
9(1.
PMID: 39774090
Background: Liver fibrosis could lead to serious secondary diseases, including osteodystrophy. The interaction between liver and bone has not been fully elucidated, thus existing therapies for osteodystrophy secondary to liver...
2.
Ishida N, Kurosawa T, Goto M, Kaji N, Tokunaga Y, Mihara T, et al.
Int J Med Sci
. 2024 Jun;
21(8):1461-1471.
PMID: 38903922
Dasatinib is one of the second-generation tyrosine kinase inhibitors used to treat chronic myeloid leukemia and has a broad target spectrum, including KIT, PDGFR, and SRC family kinases. Due to...
3.
Mihara T, Hori M
Hepatol Commun
. 2024 Jun;
8(6).
PMID: 38836815
Background: Smoking is a risk factor for liver cirrhosis; however, the underlying mechanisms remain largely unexplored. The α7 nicotinic acetylcholine receptor (α7nAChR) has recently been detected in nonimmune cells possessing...
4.
Kimura H, Yamazaki T, Mihara T, Kaji N, Kishi K, Hori M
J Vet Med Sci
. 2022 Mar;
84(4):610-617.
PMID: 35249909
Postoperative ileus (POI) is a postsurgical gastrointestinal motility dysfunction caused by mechanical stress to the intestine during abdominal surgery. POI leads to nausea and vomiting reduced patient quality of life,...
5.
Sogawa-Fujiwara C, Fujiwara Y, Hanagata A, Yang Q, Mihara T, Kaji N, et al.
BMC Res Notes
. 2021 Nov;
14(1):438.
PMID: 34838130
Objective: The biological importance for the signaling of C-type natriuretic peptide (CNP) and natriuretic peptide receptor B (NPR-B) has been recognized. However, the details remain unclear and are debatable. The...
6.
Kurosawa T, Goto M, Kaji N, Aikiyo S, Mihara T, Ikemoto-Uezumi M, et al.
Cell Death Dis
. 2021 Jan;
12(1):11.
PMID: 33414474
Liver cirrhosis is a critical health problem associated with several complications, including skeletal muscle atrophy, which adversely affects the clinical outcome of patients independent of their liver functions. However, the...
7.
Kimura H, Imura Y, Tomiyasu H, Mihara T, Kaji N, Ohno K, et al.
Sci Rep
. 2019 Apr;
9(1):5887.
PMID: 30971711
Gastrointestinal prokinetic agents function as serotonin-4 receptor (5-HTR) agonists to activate myenteric plexus neurons to release acetylcholine (ACh), which then induce anti-inflammatory action. Details of this pathway, however, remain unknown....
8.
Mikawa S, Kondo M, Kaji N, Mihara T, Yoshitake R, Nakagawa T, et al.
FASEB J
. 2018 Sep;
33(2):1669-1680.
PMID: 30207796
Antagonists of the 5-hydroxytryptamine (serotonin) 3 receptor (5-HTR) have anti-inflammatory and anti-apoptotic activities, but the detailed, underlying mechanisms are not well understood. We focused on anti-apoptotic activities via 5-HTR signaling...
9.
Mihara T, Otsubo W, Horiguchi K, Mikawa S, Kaji N, Iino S, et al.
J Vet Med Sci
. 2017 Sep;
79(11):1795-1802.
PMID: 28931778
Regulation of inflammation in intestinal mesothelial cells in the abdominal cavity is important for the pathogeny of clinical conditions, such as postoperative ileus, peritonitis and encapsulating peritoneal sclerosis. Here we...
10.
Mihara T, Mikawa S, Kaji N, Endo M, Oikawa T, Tong-Rong J, et al.
Inflammation
. 2017 May;
40(4):1331-1341.
PMID: 28493080
Postoperative ileus is a common complication after intra-abdominal surgery. Nitric oxide produced by macrophages in the inflamed gastrointestinal tract plays a crucial role in the pathogeny of postoperative ileus. Honokiol,...