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Shixiao Wang

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Articles 23
Citations 93
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Recent Articles
1.
Liu B, Wang S, Guo H, Yin H, Song Y, Gong M, et al.
Polymers (Basel) . 2025 Jan; 17(1. PMID: 39795503
Poly(glycolic acid) (PGA) is a rapidly degradable polymer mainly used in medical applications, attributed to its relatively high cost. Reducing its price will boost its utilization in a wider range...
2.
Wang S, Zhong C, Li F, Ding Z, Tang Y, Li W
Mol Divers . 2024 Apr; PMID: 38652366
Plinabulin, a 2, 5-diketopiperazine-type tubulin inhibitor derived from marine natural products, is currently undergoing Phase III clinical trials for the treatment of non-small cell lung cancer (NSCLC) and chemotherapy-induced neutropenia...
3.
Farhadi F, Wang S, Palacin R, Blythe P
iScience . 2023 Sep; 26(10):107737. PMID: 37720110
This paper presents a data-driven methodology combining simulation and multi-objective optimization to efficiently implement transportation policy commitments, using as a case study the electric vehicle (EV) charging infrastructure in Newcastle...
4.
Fang S, Bi S, Li Y, Tian S, Xu H, Fu L, et al.
Bioorg Med Chem Lett . 2023 Jun; 91:129370. PMID: 37301522
Plinabulin is a promising microtubule destabilizing agent in phase 3 clinical stage for treating non-small cell lung cancer. However, the high toxicity and the poor water solubility of plinabulin limited...
5.
Li H, Kong X, Wang S, Gong M, Lin X, Zhang L, et al.
Molecules . 2023 Apr; 28(7). PMID: 37049858
In the rapidly growing area of high-frequency communications, polyimide films with ultralow dielectric constant and dielectric loss, adequate insulating strength, and recyclability are in high demand. Using a synthesized soluble...
6.
Zhang J, Wang S, Liu B
Genes (Basel) . 2023 Feb; 14(2). PMID: 36833255
Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity for tissue regeneration, and an increased risk of age-related diseases and mortality. A variety of genetic and epigenetic...
7.
Zhao J, Yuan W, Wang S, Zhang H, Chen D, Niu X, et al.
Molecules . 2022 Dec; 27(23). PMID: 36500233
M10, a novel myricetin derivative, is an anti-inflammatory agent designed for treatment of colitis. Here, we aim to investigate its pharmacokinetic behavior and tissue distribution in a mouse model with...
8.
Wang S, Kong X, Chen N, Hu P, Boucetta H, Hu Z, et al.
Front Pharmacol . 2022 Oct; 13:1007284. PMID: 36304159
(PM) and (rhubarb) contain similar hepatocyte-toxic anthraquinones such as emodin (major free anthraquinone in PM), physcion and their glycosides. In clinical practice, PM hepatotoxicity has been widely reported, although rhubarb...
9.
Chen Y, Hu Z, Qi W, Gao S, Jiang J, Wang S, et al.
J Pharm Biomed Anal . 2020 Dec; 194:113784. PMID: 33280996
Chinese herbal drugs are often combined with chemotherapy drugs for the treatment of cancers. However, the combination administrations often do not have scientifically sound bases established on full preclinical and...
10.
Ding Z, Li F, Zhong C, Li F, Liu Y, Wang S, et al.
Bioorg Med Chem . 2020 Apr; 28(10):115435. PMID: 32278711
Plinabulin, a synthetic analog of the marine natural product "diketopiperazine phenylahistin," displayed depolymerization effects on microtubules and targeted the colchicine site, which has been moved into phase III clinical trials...