Shinji Go
Overview
Explore the profile of Shinji Go including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
311
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0
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Recent Articles
1.
Inokuchi J, Go S, Suzuki A, Nakagawasai O, Odaira-Satoh T, Veillon L, et al.
Front Neurosci
. 2024 Aug;
18:1387221.
PMID: 39119456
Ganglioside GM3 synthase is a key enzyme involved in the biosynthesis of gangliosides. GM3 synthase deficiency (GM3SD) causes an absence of GM3 and all downstream biosynthetic derivatives, including all the...
2.
Watanabe T, Tsuboi K, Matsuda N, Ishizuka Y, Go S, Watanabe E, et al.
J Neurochem
. 2023 Jun;
166(4):720-746.
PMID: 37337846
Krabbe disease is an inherited demyelinating disease caused by a genetic deficiency of the lysosomal enzyme galactosylceramide (GalCer) β-galactosidase (GALC). The Twitcher (Twi) mouse is a naturally occurring, genetically and...
3.
Watanabe T, Suzuki A, Ohira S, Go S, Ishizuka Y, Moriya T, et al.
J Lipid Res
. 2022 Nov;
63(12):100303.
PMID: 36441023
Glycosphingolipids (GSLs) are composed of a polar glycan chain and a hydrophobic tail known as ceramide. Together with variation in the glycan chain, ceramides exhibit tissue-specific structural variation in the...
4.
Inokuchi J, Go S, Hirabayashi Y
Adv Neurobiol
. 2022 Oct;
29:95-116.
PMID: 36255673
Glycoproteins carrying O-linked N-acetylgalactosamine, N-acetylglucosamine, mannose, fucose, glucose, and xylose are found in the nervous system. Lipids are glycosylated by distinct glycosylation enzymes as well. Membrane lipid, ceramide, is modified...
5.
Go S, Sato C, Hane M, Go S, Kitajima K
Glycoconj J
. 2022 May;
39(5):619-631.
PMID: 35639196
A transition of sialic acid (Sia) species on GM3 ganglioside from N-acetylneuraminic acid (Neu5Ac) to N-glycolylneuraminic acid (Neu5Gc) takes place in mouse C2C12 myoblast cells during their differentiation into myotube...
6.
Tsuboi K, Tai T, Yamashita R, Ali H, Watanabe T, Uyama T, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 May;
1866(9):158972.
PMID: 34033896
Bioactive N-acylethanolamines (NAEs) include palmitoylethanolamide, oleoylethanolamide, and anandamide, which exert anti-inflammatory, anorexic, and cannabimimetic actions, respectively. The degradation of NAEs has been attributed to two hydrolases, fatty acid amide hydrolase...
7.
Inamura N, Go S, Watanabe T, Takase H, Takakura N, Nakayama A, et al.
Brain Pathol
. 2021 Apr;
31(5):e12951.
PMID: 33822434
Krabbe disease (KD), also known as globoid cell leukodystrophy, is an inherited demyelinating disease caused by the deficiency of lysosomal galactosylceramidase (GALC) activity. Most of the patients are characterized by...
8.
Kanoh H, Nitta T, Go S, Inamori K, Veillon L, Nihei W, et al.
EMBO J
. 2020 May;
39(12):e101732.
PMID: 32378734
Innate immune signaling via TLR4 plays critical roles in pathogenesis of metabolic disorders, but the contribution of different lipid species to metabolic disorders and inflammatory diseases is less clear. GM3...
9.
Hiraoka M, Ohkawa E, Abe A, Murata M, Go S, Inokuchi J, et al.
Curr Eye Res
. 2019 Jan;
44(6):664-670.
PMID: 30688114
: Most complex gangliosides in vertebrates are formed from ganglioside GM3. GM3 deficiency in humans can result in epilepsy and visual impairment. To investigate whether a deficiency of GM3 is...
10.
Inamura N, Kito M, Go S, Kishi S, Hosokawa M, Asai K, et al.
Neurobiol Dis
. 2018 Sep;
120:51-62.
PMID: 30176352
Krabbe disease (KD), or globoid cell leukodystrophy, is an inherited lysosomal storage disease with leukodystrophy caused by a mutation in the galactosylceramidase (GALC) gene. The majority of patients show the...