Shih-Wei Chuo
Overview
Explore the profile of Shih-Wei Chuo including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
39
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chung D, Connelly E, Unnikrishnan A, Chuo S, Wucherer K, Nadel C, et al.
J Biol Chem
. 2025 Jan;
301(3):108220.
PMID: 39863102
Carboxyl-terminus of Hsp70-Interacting Protein (CHIP) is an E3 ubiquitin ligase that marks misfolded substrates for degradation. Hyper-activation of CHIP has been implicated in multiple diseases, including cystic fibrosis and cancer,...
2.
Chung D, Kong S, Young N, Chuo S, Shiah J, Connelly E, et al.
Commun Biol
. 2023 Oct;
6(1):1036.
PMID: 37828150
In vitro biopanning platforms using synthetic phage display antibody libraries have enabled the identification of antibodies against antigens that were once thought to be beyond the scope of immunization. Applying...
3.
Lourenco A, Chuo S, Bohn M, Hann B, Khan S, Yevalekar N, et al.
MAbs
. 2023 Mar;
15(1):2184197.
PMID: 36859773
The urokinase-type plasminogen activator receptor (uPAR) is an essential regulator for cell signaling in tumor cell proliferation, adhesion, and metastasis. The ubiquitous nature of uPAR in many aggressive cancer types...
4.
Hulce K, Jaishankar P, Lee G, Bohn M, Connelly E, Wucherer K, et al.
Cell Chem Biol
. 2022 Apr;
29(5):785-798.e19.
PMID: 35364007
Viruses are responsible for some of the most deadly human diseases, yet available vaccines and antivirals address only a fraction of the potential viral human pathogens. Here, we provide a...
5.
Liou S, Chuo S, Qiu Y, Wang L, Goodin D
Biochemistry
. 2020 May;
59(21):2012-2021.
PMID: 32369344
Putidaredoxin (Pdx) is the exclusive reductase and a structural effector for P450cam (CYP101A1). However, the mechanism of how Pdx modulates the conformational states of P450cam remains elusive. Here we report...
6.
Shi X, Chuo S, Liou S, Goodin D
Biochemistry
. 2020 Apr;
59(19):1823-1831.
PMID: 32338502
CYP119, a bacterial thermophilic protein from the cytochrome P450 superfamily, has previously been observed in three different conformations with different inhibitors bound using X-ray crystallography. The significance of these states...
7.
Chuo S, Liou S, Wang L, Britt R, Poulos T, Sevrioukova I, et al.
Biochemistry
. 2019 Aug;
58(37):3903-3910.
PMID: 31456404
Human cytochrome P450 3A4 (CYP3A4) is a membrane-associated monooxygenase that is responsible for metabolizing >50% of the pharmaceuticals in the current market, so studying its chemical mechanism and structural changes...
8.
Chuo S, Wang L, Britt R, Goodin D
Biochemistry
. 2019 Apr;
58(18):2353-2361.
PMID: 30994334
Cytochrome P450cam is an archetypal example of the vast family of heme monooxygenases and serves as a model for an enzyme that is highly specific for both its substrate and...
9.
Hudson W, Kossmann B, de Vera I, Chuo S, Weikum E, Eick G, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
113(2):326-31.
PMID: 26715749
Many genomes contain families of paralogs--proteins with divergent function that evolved from a common ancestral gene after a duplication event. To understand how paralogous transcription factors evolve divergent DNA specificities,...
10.
Hsu S, Lin T, Chen H, Chuo S, Kao C, Chen P, et al.
Kaohsiung J Med Sci
. 2011 Sep;
27(9):424-9.
PMID: 21914531
This study based on the synthesis, characterization, and structural calculation of small molecular potassium-encapsulated arsenic-dithiolato compounds will provide fundamental knowledge about arsenic metabolism behavior in biological system. Two novel air-stable...