Shigekazu Nagata
Overview
Explore the profile of Shigekazu Nagata including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
12427
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Recent Articles
1.
Chen X, Don A, Fedorova M, Harayama T, Krahmer N, Nagata S, et al.
Nat Cell Biol
. 2025 Feb;
27(2):169-174.
PMID: 39910286
No abstract available.
2.
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, et al.
Elife
. 2024 Nov;
13.
PMID: 39570652
Systemic lupus erythematosus (SLE) is an autoimmune disease, the pathophysiology and genetic basis of which are incompletely understood. Using a forward genetic screen in multiplex families with SLE, we identified...
3.
Calianese D, Noji T, Sullivan J, Schoch K, Shashi V, McNiven V, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(44):e2415755121.
PMID: 39432785
The maintenance of lipid asymmetry on the plasma membrane is regulated by flippases, such as ATP8A2, ATP11A, and ATP11C, which translocate phosphatidylserine and phosphatidylethanolamine from the outer leaflet to the...
4.
Miyata Y, Takahashi K, Lee Y, Sultan C, Kuribayashi R, Takahashi M, et al.
Nat Struct Mol Biol
. 2024 Oct;
32(1):185-198.
PMID: 39424995
Phospholipids are asymmetrically distributed in the plasma membrane (PM), with phosphatidylcholine and sphingomyelin abundant in the outer leaflet. However, the mechanisms by which their distribution is regulated remain unclear. Here,...
5.
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, et al.
medRxiv
. 2024 Jun;
PMID: 38883731
Systemic Lupus Erythematosus (SLE) is an autoimmune disease, the pathophysiology and genetic basis of which are incompletely understood. Using a forward genetic screen in multiplex families with systemic lupus erythematosus...
6.
Sakuragi T, Kanai R, Otani M, Kikkawa M, Toyoshima C, Nagata S
J Biol Chem
. 2024 Feb;
300(3):105755.
PMID: 38364890
XK-related 8 (XKR8), in complex with the transmembrane glycoprotein basigin, functions as a phospholipid scramblase activated by the caspase-mediated cleavage or phosphorylation of its C-terminal tail. It carries a putative...
7.
Suzuki K, Nagata S
Proc Jpn Acad Ser B Phys Biol Sci
. 2023 Aug;
99(8):227.
PMID: 37648505
No abstract available.
8.
Nagata S
Proc Jpn Acad Ser B Phys Biol Sci
. 2023 Aug;
100(1):1-14.
PMID: 37648466
In the late 1970s, crude interferon samples were found to exhibit anti-tumour activity. This discovery led to the interferon as a "magic drug" for cancer patients. Many groups, including those...
9.
Sakuragi T, Nagata S
Nat Rev Mol Cell Biol
. 2023 May;
24(8):597.
PMID: 37217623
No abstract available.
10.
Sakuragi T, Nagata S
Nat Rev Mol Cell Biol
. 2023 Apr;
24(8):576-596.
PMID: 37106071
Cellular membranes function as permeability barriers that separate cells from the external environment or partition cells into distinct compartments. These membranes are lipid bilayers composed of glycerophospholipids, sphingolipids and cholesterol,...