Yasuo Uchiyama
Overview
Explore the profile of Yasuo Uchiyama including associated specialties, affiliations and a list of published articles.
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Articles
227
Citations
21311
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Recent Articles
1.
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno S, Imamichi-Tatano Y, et al.
Nat Med
. 2025 Jan;
31(2):698.
PMID: 39856337
No abstract available.
2.
Javed R, Mari M, Trosdal E, Duque T, Paddar M, Allers L, et al.
J Cell Biol
. 2025 Jan;
224(2).
PMID: 39745851
Canonical autophagy captures within specialized double-membrane organelles, termed autophagosomes, an array of cytoplasmic components destined for lysosomal degradation. An autophagosome is completed when the growing phagophore undergoes ESCRT-dependent membrane closure,...
3.
Yamauchi S, Sugiura Y, Yamaguchi J, Zhou X, Takenaka S, Odawara T, et al.
Sci Adv
. 2024 Oct;
10(43):eado5887.
PMID: 39454000
Cellular senescence is a stress-induced irreversible cell cycle arrest involved in tumor suppression and aging. Many stresses, such as telomere shortening and oncogene activation, induce senescence by damaging nuclear DNA....
4.
Suzuki C, Yamaguchi J, Mitsui S, Sanada T, Trejo J, Kakuta S, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Sep;
1870(8):167494.
PMID: 39233262
SNCA/PARK1 encodes α-synuclein, which is associated with familial Parkinson's disease. Despite its abundance in presynaptic terminals, the aggregation mechanism of α-synuclein and its relationship with Parkinson's disease have not yet...
5.
Sou Y, Yamaguchi J, Masuda K, Uchiyama Y, Maeda Y, Koike M
Life Sci Alliance
. 2024 Jul;
7(10).
PMID: 39079741
Protein glycosylation plays a vital role in various cellular functions, many of which occur within the Golgi apparatus. The Golgi pH regulator (GPHR) is essential for the proper functioning of...
6.
Shizukuishi S, Ogawa M, Kuroda E, Hamaguchi S, Sakuma C, Kakuta S, et al.
Cell Rep
. 2024 Mar;
43(3):113962.
PMID: 38483905
Pneumolysin (Ply) is an indispensable cholesterol-dependent cytolysin for pneumococcal infection. Although Ply-induced disruption of pneumococci-containing endosomal vesicles is a prerequisite for the evasion of endolysosomal bacterial clearance, its potent activity...
7.
Murakami S, Ohki-Hamazaki H, Uchiyama Y
Dev Neurobiol
. 2023 Dec;
84(1):3-17.
PMID: 38072668
Transient expression of somatostatin (SST) has been observed in the olfactory epithelium (OE) and nerves of chick embryos. Intense expression of SST in these regions on embryonic days (E) 5-8...
8.
Verhoeven J, Jacobs K, Rizzollo F, Lodi F, Hua Y, Pozniak J, et al.
EMBO Mol Med
. 2023 Nov;
15(12):e18028.
PMID: 38009521
Tumor endothelial cells (TECs) actively repress inflammatory responses and maintain an immune-excluded tumor phenotype. However, the molecular mechanisms that sustain TEC-mediated immunosuppression remain largely elusive. Here, we show that autophagy...
9.
Kameyama T, Miyata M, Shiotani H, Adachi J, Kakuta S, Uchiyama Y, et al.
iScience
. 2023 Oct;
26(10):108010.
PMID: 37829206
Astrocytes interact with not only synapses but also brain blood vessels through perivascular astrocyte endfeet (PV-AEF) to form the neurovascular unit (NVU). However, PV-AEF components have not been fully identified....
10.
Mitsui S, Yamaguchi J, Suzuki C, Uchiyama Y, Tanida I
Glia
. 2023 Aug;
71(12):2753-2769.
PMID: 37571859
Neuronal ceroid lipofuscinosis is a group of pediatric neurodegenerative diseases. One of their causative genes, CLN10/CtsD, encodes cathepsin D, a major lysosomal protease. Central nervous system (CNS)-specific CtsD-deficient mice exhibit...