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Rikinari Hanayama

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Articles 52
Citations 3027
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Recent Articles
1.
Ida H, Yoshida T, Kumatani A, Hanayama R, Takahashi Y
Nano Lett . 2025 Feb; PMID: 40015929
Because endogenous extracellular vesicles are involved in important physiological functions, various techniques have been developed for their isolation and evaluation. However, methods for evaluating endogenous vesicles within cells are limited....
2.
Li Y, Hirayasu K, Hasegawa G, Tomita Y, Hashikawa Y, Hiwa R, et al.
Front Immunol . 2024 Oct; 15:1435236. PMID: 39376567
The leukocyte immunoglobulin-like receptor (LILR) family, a group of primate-specific immunoreceptors, is widely expressed on most immune cells and regulates immune responses through interactions with various ligands. The inhibitory type,...
3.
Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, et al.
Nat Cell Biol . 2024 Aug; 26(9):1558-1570. PMID: 39174742
Cells release intraluminal vesicles in multivesicular bodies as exosomes to communicate with other cells. Although recent studies suggest an intimate link between exosome biogenesis and autophagy, the detailed mechanism is...
4.
Zaimoku Y, Sakai K, Tsuji N, Hosomichi K, Yamada S, Tran D, et al.
Br J Haematol . 2024 Aug; 205(5):1995-1999. PMID: 39155468
We describe the case of a 74-year-old man with severe aplastic anaemia who experienced persistent remission attributed to proliferation of HLA allele-deficient clones. Despite an initial worsening of pancytopenia with...
5.
Takakura Y, Hanayama R, Akiyoshi K, Futaki S, Hida K, Ichiki T, et al.
Pharm Res . 2024 Aug; 41(8):1573-1594. PMID: 39112776
Extracellular vesicles (EVs) serve as an intrinsic system for delivering functional molecules within our body, playing significant roles in diverse physiological phenomena and diseases. Both native and engineered EVs are...
6.
Hirayasu K, Khor S, Kawai Y, Shimada M, Omae Y, Hasegawa G, et al.
Front Immunol . 2024 May; 15:1398935. PMID: 38807600
Leukocyte immunoglobulin (Ig)-like receptors (LILRs) on human chromosome 19q13.4 encode 11 immunoglobulin superfamily receptors, exhibiting genetic diversity within and between human populations. Among the genes, the genomic region surrounding and...
7.
Hori A, Toyoura S, Fujiwara M, Taniguchi R, Kano Y, Yamano T, et al.
iScience . 2024 Apr; 27(5):109704. PMID: 38680663
In addition to cross-presentation, cross-dressing plays an important role in the induction of CD8 T cell immunity. In the process of cross-dressing, conventional dendritic cells (DCs) acquire major histocompatibility complex...
8.
Kobayashi H, Shiba T, Yoshida T, Bolidong D, Kato K, Sato Y, et al.
Sci Rep . 2024 Mar; 14(1):7465. PMID: 38553534
Methods that enable specific and sensitive quantification of small extracellular vesicles (sEVs) using flow cytometry are still under development. Aggregation or adsorption of antibodies causes sub-nano sized particles or non-specific...
9.
Yoshida T, Goto K, Kodama A, Bolidong D, Seto T, Hanayama R
Arch Biochem Biophys . 2024 Mar; 755:109964. PMID: 38527699
Amorphous silica has been approved as a food and pharmaceutical additive. However, its potential to enhance the carcinogenicity of epithelial cells is incontrovertible. With their expanded surface area per unit...
10.
Dochi H, Kondo S, Komura S, Moriyama-Kita M, Komori T, Nanbo A, et al.
Int J Cancer . 2023 Nov; 154(5):895-911. PMID: 37907830
Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) cells have high metastatic potential. Recent research has revealed that the interaction of between tumor cells and the surrounding stroma plays an important role...