Sherman Weissman
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Explore the profile of Sherman Weissman including associated specialties, affiliations and a list of published articles.
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35
Citations
6225
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Recent Articles
1.
Zhang W, Huckaby B, Talburt J, Weissman S, Yang M
Sci Rep
. 2024 Feb;
14(1):3946.
PMID: 38365936
The advent of single-cell RNA sequencing (scRNA-seq) technology has revolutionized our ability to explore cellular diversity and unravel the complexities of intricate diseases. However, due to the inherently low signal-to-noise...
2.
Abyzov A, Tomasini L, Zhou B, Vasmatzis N, Coppola G, Amenduni M, et al.
Genome Res
. 2017 Feb;
27(4):512-523.
PMID: 28235832
Few studies have been conducted to understand post-zygotic accumulation of mutations in cells of the healthy human body. We reprogrammed 32 skin fibroblast cells from families of donors into human...
3.
Akbarian S, Liu C, Knowles J, Vaccarino F, Farnham P, Crawford G, et al.
Nat Neurosci
. 2015 Nov;
18(12):1707-12.
PMID: 26605881
No abstract available.
4.
Rivera-Mulia J, Buckley Q, Sasaki T, Zimmerman J, Didier R, Nazor K, et al.
Genome Res
. 2015 Jun;
25(8):1091-103.
PMID: 26055160
Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically during development, regulated in units of 400-800...
5.
Liu L, Karmakar S, Dhar R, Mahajan M, Choudhury A, Weissman S, et al.
PLoS One
. 2013 Nov;
8(11):e78253.
PMID: 24223142
The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in...
6.
Zhang Y, Haraksingh R, Grubert F, Abyzov A, Gerstein M, Weissman S, et al.
Child Dev
. 2013 Jan;
84(1):34-48.
PMID: 23311762
Structural variation of the human genome sequence is the insertion, deletion, or rearrangement of stretches of DNA sequence sized from around 1,000 to millions of base pairs. Over the past...
7.
Abyzov A, Mariani J, Palejev D, Zhang Y, Haney M, Tomasini L, et al.
Nature
. 2012 Nov;
492(7429):438-42.
PMID: 23160490
Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) has been suspected of causing de novo copy number variation. To explore this issue, here we perform a whole-genome and transcriptome...
8.
Wu J, Seay M, Schulz V, Hariharan M, Tuck D, Lian J, et al.
PLoS Genet
. 2012 Mar;
8(3):e1002565.
PMID: 22412390
A critical problem in biology is understanding how cells choose between self-renewal and differentiation. To generate a comprehensive view of the mechanisms controlling early hematopoietic precursor self-renewal and differentiation, we...
9.
Wontakal S, Guo X, Will B, Shi M, Raha D, Mahajan M, et al.
PLoS Genet
. 2011 Jun;
7(6):e1001392.
PMID: 21695229
PU.1 is a hematopoietic transcription factor that is required for the development of myeloid and B cells. PU.1 is also expressed in erythroid progenitors, where it blocks erythroid differentiation by...
10.
Vaccarino F, Stevens H, Kocabas A, Palejev D, Szekely A, Grigorenko E, et al.
Neuropharmacology
. 2011 Mar;
60(7-8):1355-63.
PMID: 21371482
Studies in the area of human brain development are critical as research on neurological and psychiatric disorders has advanced, revealing the origins of pathophysiology to be in the earliest developmental...