Sherman M Weissman
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Explore the profile of Sherman M Weissman including associated specialties, affiliations and a list of published articles.
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71
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5756
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Recent Articles
1.
Mai L, Wen Z, Zhang Y, Gao Y, Lin G, Lian Z, et al.
Nucleic Acids Res
. 2023 Oct;
51(21):e108.
PMID: 37870443
DNA methylation is essential for a wide variety of biological processes, yet the development of a highly efficient and robust technology remains a challenge for routine single-cell analysis. We developed...
2.
Ma J, Pettit N, Talburt J, Wang S, Weissman S, Yang M
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430822
Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by a unique BCR-ABL fusion gene. Tyrosine kinase inhibitors (TKIs) were developed to target the BCR-ABL oncoprotein, inhibiting its abnormal kinase...
3.
Zhang Y, Xu S, Wen Z, Gao J, Li S, Weissman S, et al.
Cell Mol Life Sci
. 2022 Aug;
79(8):466.
PMID: 35927335
Single-cell sequencing is widely used in biological and medical studies. However, its application with multiple samples is hindered by inefficient sample processing, high experimental costs, ambiguous identification of true single...
4.
Lu Y, Liu M, Yang J, Weissman S, Pan X, Katz S, et al.
Cell Discov
. 2021 Jun;
7(1):47.
PMID: 34183665
The hematopoietic stem cell (HSC) niche has been extensively studied in bone marrow, yet a more systematic investigation into the microenvironment regulation of hematopoiesis in fetal liver is necessary. Here...
5.
Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, et al.
Adv Sci (Weinh)
. 2021 Apr;
8(8):2004320.
PMID: 33898197
Cancer stem cells (CSCs) presumably contribute to tumor progression and drug resistance, yet their definitive features have remained elusive. Here, simultaneous measurement of telomere length and transcriptome in the same...
6.
Xiang Y, Tanaka Y, Patterson B, Hwang S, Hysolli E, Cakir B, et al.
Mol Cell
. 2020 Jun;
79(1):84-98.e9.
PMID: 32526163
Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here, we used 2D and 3D...
7.
Zhang J, Spath S, Weissman S, Katz S
Methods Mol Biol
. 2019 Nov;
2097:139-171.
PMID: 31776925
Tumors have a complex ecosystem in which behavior and fate are determined by the interaction of diverse cancerous and noncancerous cells at local and systemic levels. A number of studies...
8.
Rabinovich P, Zhang J, Kerr S, Cheng B, Komarovskaya M, Bersenev A, et al.
J Immunol Methods
. 2019 Sep;
474:112668.
PMID: 31525367
Cell-mediated cytotoxicity is a critical function of the immune system in mounting defense against pathogens and cancers. Current methods that allow direct evaluation of cell-mediated cytotoxicity suffer from a wide-range...
9.
Gong P, Wang H, Zhang J, Fu Y, Zhu Z, Wang J, et al.
Transl Oncol
. 2019 Jun;
12(9):1164-1176.
PMID: 31207547
Telomere length maintenance is essential for cell proliferation, which is particularly prominent in cancer. We validate that the primary colorectal tumors exhibit heterogeneous telomere lengths but mostly (90%) short telomeres...
10.
Xiang Y, Tanaka Y, Cakir B, Patterson B, Kim K, Sun P, et al.
Cell Stem Cell
. 2019 Feb;
24(3):487-497.e7.
PMID: 30799279
Human brain organoid techniques have rapidly advanced to facilitate investigating human brain development and diseases. These efforts have largely focused on generating telencephalon due to its direct relevance in a...