Sherman M Weissman
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Explore the profile of Sherman M Weissman including associated specialties, affiliations and a list of published articles.
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71
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5756
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Recent Articles
11.
Yang M, Weissman S, Yang W, Zhang J, Canaan A, Guan R
BMC Syst Biol
. 2019 Jan;
13(1):13.
PMID: 30670065
It was highlighted that the original article [1] contained a typesetting error in the last name of Allon Canaan. This was incorrectly captured as Allon Canaann in the original article...
12.
Zhang X, Zhang Y, Zhu X, Purmann C, Haney M, Ward T, et al.
Nat Commun
. 2018 Dec;
9(1):5356.
PMID: 30559385
Large copy number variants (CNVs) in the human genome are strongly associated with common neurodevelopmental, neuropsychiatric disorders such as schizophrenia and autism. Here we report on the epigenomic effects of...
13.
Yang M, Weissman S, Yang W, Zhang J, Canaann A, Guan R
BMC Syst Biol
. 2018 Dec;
12(Suppl 7):114.
PMID: 30547798
Background: Single-cell RNA sequencing (scRNA-seq) technology provides an effective way to study cell heterogeneity. However, due to the low capture efficiency and stochastic gene expression, scRNA-seq data often contains a...
14.
Stanton K, Jin J, Lederman R, Weissman S, Kluger Y
Nucleic Acids Res
. 2017 Oct;
45(21):e173.
PMID: 28981893
With the advent of next generation high-throughput DNA sequencing technologies, omics experiments have become the mainstay for studying diverse biological effects on a genome wide scale. Chromatin immunoprecipitation (ChIP-seq) is...
15.
Xiang Y, Tanaka Y, Patterson B, Kang Y, Govindaiah G, Roselaar N, et al.
Cell Stem Cell
. 2017 Aug;
21(3):383-398.e7.
PMID: 28757360
Organoid techniques provide unique platforms to model brain development and neurological disorders. Whereas several methods for recapitulating corticogenesis have been described, a system modeling human medial ganglionic eminence (MGE) development,...
16.
Zhu X, Ching T, Pan X, Weissman S, Garmire L
PeerJ
. 2017 Jan;
5:e2888.
PMID: 28133571
Single-cell RNA-Sequencing (scRNA-Seq) is a fast-evolving technology that enables the understanding of biological processes at an unprecedentedly high resolution. However, well-suited bioinformatics tools to analyze the data generated from this...
17.
Han L, Wu H, Zhu H, Kim K, Marjani S, Riester M, et al.
Nucleic Acids Res
. 2017 Jan;
45(10):e77.
PMID: 28126923
Conventional DNA bisulfite sequencing has been extended to single cell level, but the coverage consistency is insufficient for parallel comparison. Here we report a novel method for genome-wide CpG island...
18.
Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family
Hysolli E, Tanaka Y, Su J, Kim K, Zhong T, Janknecht R, et al.
Stem Cell Reports
. 2016 Jul;
7(1):43-54.
PMID: 27373925
Reprogramming to pluripotency after overexpression of OCT4, SOX2, KLF4, and MYC is accompanied by global genomic and epigenomic changes. Histone modification and DNA methylation states in induced pluripotent stem cells...
19.
Cheng J, Roden C, Pan W, Zhu S, Baccei A, Pan X, et al.
Nat Commun
. 2016 Mar;
7:11178.
PMID: 27025950
Clustered regularly-interspaced palindromic repeats (CRISPR)-based genetic screens using single-guide-RNA (sgRNA) libraries have proven powerful to identify genetic regulators. Applying CRISPR screens to interrogate functional elements in noncoding regions requires generating...
20.
Zhang X, Marjani S, Hu Z, Weissman S, Pan X, Wu S
Cancer Res
. 2016 Mar;
76(6):1305-12.
PMID: 26941284
Advances in genomic technology have enabled the faithful detection and measurement of mutations and the gene expression profile of cancer cells at the single-cell level. Recently, several single-cell sequencing methods...