Shazib Pervaiz
Overview
Explore the profile of Shazib Pervaiz including associated specialties, affiliations and a list of published articles.
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Articles
145
Citations
11360
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Recent Articles
1.
Balamurli G, Liew A, Tee W, Pervaiz S
Redox Biol
. 2024 Nov;
78:103441.
PMID: 39612910
There is accumulating evidence indicating a close crosstalk between key molecular events regulating cell growth and proliferation, which could profoundly impact carcinogenesis and its progression. Here we focus on reviewing...
2.
Hirpara J, Thuya W, Cheow S, Fernando K, Eu J, Wang L, et al.
Theranostics
. 2024 Oct;
14(16):6350-6369.
PMID: 39431017
Growing evidence points to the tumor microenvironment's role in developing drug resistance. A key element of this microenvironment is inter-cellular communication, which includes the release of membrane-encapsulated vesicles containing various...
3.
Bellot G, Liu D, Fivaz M, Yadav S, Kaur C, Pervaiz S
Cell Commun Signal
. 2024 Oct;
22(1):509.
PMID: 39427179
Acquired drug resistance is a major challenge in the management of cancer, which underscores the need for discovery and development of novel therapeutic strategies. We report here the mechanism of...
4.
Amali A, Paramasivam K, Huang C, Joshi A, Hirpara J, Ravikumar S, et al.
Front Immunol
. 2024 Sep;
15:1423086.
PMID: 39224595
Molecular chaperons stabilize protein folding and play a vital role in maintaining tissue homeostasis. To this intent, mitochondrial molecular chaperons may be involved in the regulation of oxidative phosphorylation and...
5.
Lee B, Chuah Y, Yoon J, Grinchuk O, Liang Y, Hirpara J, et al.
Cell Death Dis
. 2024 Jul;
15(7):547.
PMID: 39085240
No abstract available.
6.
Lee B, Chuah Y, Yoon J, Grinchuk O, Liang Y, Hirpara J, et al.
Cell Death Dis
. 2024 May;
15(5):338.
PMID: 38744809
Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (mC) is a new epitranscriptomic mark on RNAs and...
7.
Lee Y, Chen L, Chew V, Chow E, Deng L, Hunziker W, et al.
Cancer Res
. 2024 Apr;
84(8):1195-1198.
PMID: 38616656
The 15th annual Frontiers in Cancer Science (FCS) conference gathered scientific experts who shared the latest research converging upon several themes of cancer biology. These themes included the dysregulation of...
8.
Iskandar K, Foo J, Liew A, Zhu H, Raman D, Hirpara J, et al.
Autophagy
. 2024 Jan;
20(6):1418-1441.
PMID: 38261660
RAS is one of the most commonly mutated oncogenes associated with multiple cancer hallmarks. Notably, RAS activation induces intracellular reactive oxygen species (ROS) generation, which we previously demonstrated as a...
9.
Lau H, Tan V, Tan B, Sim Y, Quist J, Thike A, et al.
NPJ Breast Cancer
. 2023 Oct;
9(1):84.
PMID: 37863888
Despite our understanding of the genetic basis of intra-tumoral heterogeneity, the role of stromal heterogeneity arising from an altered tumor microenvironment in affecting tumorigenesis is poorly understood. In particular, extensive...
10.
Chong S, Zhu F, Dashevsky O, Mizuno R, Lai J, Hackett L, et al.
J Clin Invest
. 2023 Sep;
133(22).
PMID: 37751299
The B cell leukemia/lymphoma 2 (BCL-2) inhibitor venetoclax is effective in chronic lymphocytic leukemia (CLL); however, resistance may develop over time. Other lymphoid malignancies such as diffuse large B cell...