Sharad C Paudyal
Overview
Explore the profile of Sharad C Paudyal including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
236
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0
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Recent Articles
1.
Wang L, Paudyal S, Kang Y, Owa M, Liang F, Spektor A, et al.
Cell Res
. 2021 Nov;
32(2):190-209.
PMID: 34782749
Cytoskeletal networks play an important role in regulating nuclear morphology and ciliogenesis. However, the role of microtubule (MT) post-translational modifications in nuclear shape regulation and cilium disassembly has not been...
2.
Chung J, Goldstein L, Chen Y, Lee J, Webster J, Roose-Girma M, et al.
J Am Soc Nephrol
. 2020 Jul;
31(10):2341-2354.
PMID: 32651223
Background: The glomerulus is a specialized capillary bed that is involved in urine production and BP control. Glomerular injury is a major cause of CKD, which is epidemic and without...
3.
Paudyal S, Li S, Yan H, Hunter T, You Z
Nucleic Acids Res
. 2017 Oct;
45(20):11766-11781.
PMID: 28981724
Nucleolytic resection of DNA double-strand breaks (DSBs) is essential for both checkpoint activation and homology-mediated repair; however, the precise mechanism of resection, especially the initiation step, remains incompletely understood. Resection...
4.
Paudyal S, You Z
Acta Biochim Biophys Sin (Shanghai)
. 2016 May;
48(7):647-57.
PMID: 27174871
DNA end resection is a key process in the cellular response to DNA double-strand break damage that is essential for genome maintenance and cell survival. Resection involves selective processing of...
5.
Cheruiyot A, Paudyal S, Kim I, Sparks M, Ellenberger T, Piwnica-Worms H, et al.
DNA Repair (Amst)
. 2015 Nov;
35:106-15.
PMID: 26519824
Exonuclease 1 (Exo1) has important roles in DNA metabolic transactions that are essential for genome maintenance, telomere regulation and cancer suppression. However, the mechanisms for regulating Exo1 activity in these...
6.
Chen X, Kim I, Honaker Y, Paudyal S, Koh W, Sparks M, et al.
J Biol Chem
. 2015 Apr;
290(19):12300-12.
PMID: 25833945
The DNA end resection process dictates the cellular response to DNA double strand break damage and is essential for genome maintenance. Although insufficient DNA resection hinders homology-directed repair and ATR...
7.
Chen X, Paudyal S, Chin R, You Z
Nucleic Acids Res
. 2013 Aug;
41(20):9325-38.
PMID: 23939618
Exo1-mediated resection of DNA double-strand break ends generates 3' single-stranded DNA overhangs required for homology-based DNA repair and activation of the ATR-dependent checkpoint. Despite its critical importance in inducing the...
8.
Liu C, Wu J, Paudyal S, You Z, Yu X
Nucleic Acids Res
. 2012 Dec;
41(3):1698-710.
PMID: 23268447
Protein ubiquitination plays an important role in activating the DNA damage response and maintaining genomic stability. In response to DNA double-strand breaks (DSBs), a ubiquitination cascade occurs at DNA lesions....