Shanli Tsui
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Explore the profile of Shanli Tsui including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
486
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Recent Articles
1.
Tsui S, Wang J, Wang L, Dai W, Lu L
PLoS One
. 2016 Sep;
11(9):e0162071.
PMID: 27583466
Background: The purpose of the study is to elicit the epigenetic mechanism involving CCCTC binding factor (CTCF)-mediated chromatin remodeling that regulates PAX6 gene interaction with differentiation-associated genes to control corneal...
2.
Hoa N, Tsui S, Afifiyan N, Hikim A, Li B, Douglas R, et al.
PLoS One
. 2012 Apr;
7(4):e34173.
PMID: 22506015
Insulin-like growth factor-1 receptor (IGF-1R) comprises two subunits, including a ligand binding domain on extra- cellular IGF-1Rα and a tyrosine phosphorylation site located on IGF-1Rβ. IGF-1R is over-expressed by orbital...
3.
Tsui S, Gao J, Wang C, Lu L
Exp Cell Res
. 2012 Mar;
318(8):887-95.
PMID: 22426149
Pancreatic islet α-cell development and glucagon production are mainly regulated by Pax6 in the homeobox gene families. However, the molecular mechanism fine-tuning the regulation of these events in α-cell still...
4.
Narayan R, Nguyen H, Bentow J, Moy L, Lee D, Greger S, et al.
J Invest Dermatol
. 2011 Aug;
132(1):163-9.
PMID: 21850019
Imiquimod is a synthetic Toll-like receptor 7 (TLR7) agonist approved for the topical treatment of actinic keratoses, superficial basal cell carcinoma, and genital warts. Imiquimod leads to an 80-100% cure...
5.
Zhao S, Tsui S, Cheung A, Douglas R, Smith T, Banga J
J Endocrinol
. 2011 Jul;
210(3):369-77.
PMID: 21715431
The TSH receptor (TSHR) is the critical target for antibody production in Graves' disease (GD). Insulin-like growth factor 1 receptor (IGF1R) has been proposed as a second autoantigen in complications...
6.
Tsui S, Fernando R, Chen B, Smith T
J Biol Chem
. 2011 May;
286(27):24487-99.
PMID: 21576248
UDP-glucose dehydrogenase (UGDH) catalyzes the formation of UDP-glucuronate. Glucuronate represents an integral component of the glycosaminoglycan, hyaluronan, which accumulates in orbital Graves disease. Here we report that orbital fibroblasts express...
7.
Smith T, Tsai C, Shih M, Tsui S, Chen B, Han R, et al.
Thyroid
. 2008 Sep;
18(9):983-8.
PMID: 18788919
Tissue remodeling associated with thyroid-associated ophthalmopathy (TAO) involves the complex interplay between resident cells (endothelium, vascular smooth muscle, extraocular muscle, and fibroblasts) and those recruited to the orbit, including members...
8.
Tsui S, Naik V, Hoa N, Hwang C, Afifiyan N, Hikim A, et al.
J Immunol
. 2008 Sep;
181(6):4397-405.
PMID: 18768899
Thyroid-stimulating hormone receptor (TSHR) plays a central role in regulating thyroid function and is targeted by IgGs in Graves' disease (GD-IgG). Whether TSHR is involved in the pathogenesis of thyroid-associated...
9.
Chen B, Tsui S, Boeglin W, Douglas R, Brash A, Smith T
J Biol Chem
. 2006 May;
281(27):18296-306.
PMID: 16675443
Orbital fibroblasts orchestrate tissue remodeling in Graves disease, at least in part, because they exhibit exaggerated responses to proinflammatory cytokines. A hallmark of late stage orbital disease is vision-threatening fibrosis,...
10.
Chen B, Tsui S, Smith T
J Immunol
. 2005 Jul;
175(2):1310-9.
PMID: 16002736
Human orbital fibroblasts exhibit a unique inflammatory phenotype. In the present study, we report that these fibroblasts, when treated with IL-1beta, express high levels of IL-6, a cytokine involved in...