Shahzad Nawaz Syed
Overview
Explore the profile of Shahzad Nawaz Syed including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
234
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Recent Articles
1.
Syed S, Brune B
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35562884
MicroRNAs have been projected as promising tools for diagnostic and prognostic purposes in cancer. More recently, they have been highlighted as RNA therapeutic targets for cancer therapy. Though miRs perform...
2.
Raue R, Frank A, Fuhrmann D, Cruz-Ojeda P, Rosser S, Bauer R, et al.
Biology (Basel)
. 2022 Mar;
11(3).
PMID: 35336722
Macrophages constitute a major part of the tumor-infiltrating immune cells. Within the tumor microenvironment, they acquire an alternatively activated, tumor-supporting phenotype. Factors released by tumor cells are crucial for the...
3.
Frank A, Raue R, Fuhrmann D, Sirait-Fischer E, Reuse C, Weigert A, et al.
Theranostics
. 2021 Jun;
11(15):7570-7588.
PMID: 34158867
: Glucose metabolism in the tumor-microenvironment is a fundamental hallmark for tumor growth and intervention therein remains an attractive option for anti-tumor therapy. Whether tumor-derived factors such as microRNAs (miRs)...
4.
Raue R, Frank A, Syed S, Brune B
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33672261
The tumor-microenvironment (TME) is an amalgamation of various factors derived from malignant cells and infiltrating host cells, including cells of the immune system. One of the important factors of the...
5.
Syed S, Weigert A, Brune B
Int J Mol Sci
. 2020 Jul;
21(13).
PMID: 32630814
Recent studies suggested an important contribution of sphingosine-1-phospate (S1P) signaling via its specific receptors (S1PRs) in the production of pro-inflammatory mediators such as Interleukin (IL)-1β in cancer and inflammation. In...
6.
Syed S, Brune B
Cancers (Basel)
. 2020 Apr;
12(4).
PMID: 32276464
A myriad of signaling molecules in a heuristic network of the tumor microenvironment (TME) pose a challenge and an opportunity for novel therapeutic target identification in human cancers. MicroRNAs (miRs),...
7.
Syed S, Frank A, Raue R, Brune B
Cells
. 2019 Nov;
8(12).
PMID: 31766495
MicroRNAs (miRs) significantly contribute to the regulation of gene expression, by virtue of their ability to interact with a broad, yet specific set of target genes. MiRs are produced and...
8.
Syed S, Raue R, Weigert A, von Knethen A, Brune B
Cells
. 2019 Jul;
8(8).
PMID: 31357710
The bioactive lipid sphingosine-1-phosphate (S1P), along with its receptors, modulates lymphocyte trafficking and immune responses to regulate skin inflammation. Macrophages are important in the pathogenesis of psoriasiform skin inflammation and...
9.
Frank A, Ebersberger S, Fink A, Lampe S, Weigert A, Schmid T, et al.
Nat Commun
. 2019 Mar;
10(1):1135.
PMID: 30850595
Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred and how they affect their target landscape, especially in...
10.
Gupta S, Jain A, Syed S, Snodgrass R, Pfluger-Muller B, Leisegang M, et al.
Oncoimmunology
. 2018 Oct;
7(10):e1494110.
PMID: 30288360
Macrophages in the tumor microenvironment respond to complex cytokine signals. How these responses shape the phenotype of tumor-associated macrophages (TAMs) is incompletely understood. Here we explored how cytokines of the...