Andreas Weigert
Overview
Explore the profile of Andreas Weigert including associated specialties, affiliations and a list of published articles.
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Articles
216
Citations
4875
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Recent Articles
1.
Ciurus S, Elewa M, Palmer M, Wolf A, Hector M, Fuhrmann D, et al.
Cell Mol Life Sci
. 2025 Feb;
82(1):85.
PMID: 39985685
Chronic inflammatory diseases are a significant global burden and are associated with dysregulated resolution of inflammation. Therefore, promoting the process of resolution is a promising therapeutic approach. This study presents...
2.
Hernandez-Olmos V, Heering J, Ildefeld N, Ehrler J, Kaps A, Rajkumar R, et al.
J Med Chem
. 2025 Jan;
68(2):1195-1221.
PMID: 39803894
The leukotriene B4 receptor 2 (BLT2) is a G-protein coupled receptor, which is endogenously activated by 12()-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT). BLT2 is gaining attention as a potential therapeutic target involved in...
3.
Kiprina A, Teichmann T, Gimenez V, Xu W, Sailer F, Windbergs M, et al.
Front Pharmacol
. 2025 Jan;
15:1528759.
PMID: 39759451
Introduction: Anandamide (AEA) is an endocannabinoid that has recently been recognized as a regulator of various inflammatory diseases as well as cancer. While AEA was thought to predominantly engage cannabinoid...
4.
Kunze R, Wacker P, Breuer P, Nasyrov E, Kur I, Weigert A, et al.
Acta Neuropathol Commun
. 2024 Dec;
12(1):200.
PMID: 39710754
Severity and outcome of strokes following cerebral hypoperfusion are significantly influenced by stress responses of the blood vessels. In this context, brain endothelial cells (BEC) regulate inflammation, angiogenesis and the...
5.
Teichmann T, Pfluger-Muller B, Gimenez V, Sailer F, Dirks H, Zehr S, et al.
Br J Pharmacol
. 2024 Nov;
182(5):1164-1182.
PMID: 39563075
Background And Purpose: Endocannabinoids are lipid mediators, which elicit complex biological effects that extend beyond the central nervous system. Tissue concentrations of endocannabinoids increase in atherosclerosis, and for the endocannabinoid...
6.
Becker A, Rohrich K, Leske A, Heinicke U, Knape T, Kannt A, et al.
Immunotargets Ther
. 2024 Nov;
13:595-616.
PMID: 39507298
Background: COVID-19 is a serious viral infection, which is often associated with a lethal outcome. Therefore, understanding mechanisms, which affect the immune response during SARS-CoV2 infection, are important. Methods: To...
7.
Herhaus L, Gestal-Mato U, Eapen V, Macinkovic I, Bailey H, Prieto-Garcia C, et al.
Cell
. 2024 Oct;
187(25):7285-7302.e29.
PMID: 39481378
The autophagy-lysosome system directs the degradation of a wide variety of cargo and is also involved in tumor progression. Here, we show that the immunity-related GTPase family Q protein (IRGQ),...
8.
Klotz L, Weigert A, Eichhorn F, Allgauer M, Muley T, Shah R, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39410037
Immunotherapy has significantly improved overall survival in patients with pleural mesothelioma, yet this benefit does not extend to those with the epithelioid subtype. Tumor growth is believed to be influenced...
9.
Li X, Kempf S, Delgado Lagos F, Ukan U, Popp R, Hu J, et al.
iScience
. 2024 Oct;
27(10):110938.
PMID: 39398242
Fatty acid metabolites, produced by cytochrome P450 enzymes and soluble epoxide hydrolase (sEH), regulate inflammation. Here, we report that the transforming growth factor β (TGF-β)-induced polarization of macrophages to a...
10.
Weiss L, Warwick T, Zehr S, Gunther S, Wolf S, Schmachtel T, et al.
Commun Biol
. 2024 Sep;
7(1):1131.
PMID: 39271940
Monocytes, the circulating macrophage precursors, contribute to diseases like atherosclerosis and asthma. Long non-coding RNAs (lncRNAs) have been shown to modulate the phenotype and inflammatory capacity of monocytes. We previously...