Dominik C Fuhrmann
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Explore the profile of Dominik C Fuhrmann including associated specialties, affiliations and a list of published articles.
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37
Citations
730
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Recent Articles
1.
Ciurus S, Elewa M, Palmer M, Wolf A, Hector M, Fuhrmann D, et al.
Cell Mol Life Sci
. 2025 Feb;
82(1):85.
PMID: 39985685
Chronic inflammatory diseases are a significant global burden and are associated with dysregulated resolution of inflammation. Therefore, promoting the process of resolution is a promising therapeutic approach. This study presents...
2.
Wickert A, Schwantes A, Fuhrmann D, Brune B
Front Pharmacol
. 2024 Oct;
15:1474285.
PMID: 39372215
Ferroptosis is an iron-dependent form of cell death, which finally culminates in lipid peroxidation and membrane damage. During the past decade, the interest in ferroptosis increased substantially and various regulatory...
3.
Yildirim N, Sarojam L, Smith V, Pieper N, Anders M, Jackson R, et al.
Cell Death Dis
. 2024 Apr;
15(4):266.
PMID: 38622118
BH3-mimetics represent promising anti-cancer agents in tumors that rely on the anti-apoptotic function of B-Cell Lymphoma 2 (BCL2) proteins, particularly in leukemia and lymphoma cells primed for apoptosis. Mechanistically, BH3-mimetics...
4.
Benatzy Y, Palmer M, Lutjohann D, Ohno R, Kampschulte N, Schebb N, et al.
Redox Biol
. 2024 Apr;
72:103149.
PMID: 38581859
Macrophage cholesterol homeostasis is crucial for health and disease and has been linked to the lipid-peroxidizing enzyme arachidonate 15-lipoxygenase type B (ALOX15B), albeit molecular mechanisms remain obscure. We performed global...
5.
Schwantes A, Wickert A, Becker S, Baer P, Weigert A, Brune B, et al.
Redox Biol
. 2024 Feb;
71:103093.
PMID: 38382185
Solid tumors are characterized by hypoxic areas, which are prone for macrophage infiltration. Once infiltrated, macrophages polarize to tumor associated macrophages (TAM) to support tumor progression. Therefore, the crosstalk between...
6.
Alcober-Boquet L, Kraus N, Huber L, Vutukuri R, Fuhrmann D, Stross C, et al.
Am J Physiol Cell Physiol
. 2024 Jan;
326(3):C880-C892.
PMID: 38223924
17-β-hydroxysteroid dehydrogenase 13 (HSD17B13), a lipid droplet-associated enzyme, is primarily expressed in the liver and plays an important role in lipid metabolism. Targeted inhibition of enzymatic function is a potential...
7.
Drekolia M, Karantanou C, Wittig I, Li Y, Fuhrmann D, Brune B, et al.
Redox Biol
. 2024 Jan;
69:103014.
PMID: 38171255
Protein persulfidation is a significant post-translational modification that involves addition of a sulfur atom to the cysteine thiol group and is facilitated by sulfide species. Persulfidation targets reactive cysteine residues...
8.
Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Susser S, et al.
Leukemia
. 2023 Nov;
37(12):2367-2382.
PMID: 37935978
High metabolic flexibility is pivotal for the persistence and therapy resistance of acute myeloid leukemia (AML). In 20-30% of AML patients, activating mutations of FLT3, specifically FLT3-ITD, are key therapeutic...
9.
Mayr F, Kruse V, Fuhrmann D, Wolf S, Lober J, Alsouri S, et al.
Haematologica
. 2023 Nov;
109(5):1445-1459.
PMID: 37916396
Burkitt lymphoma cells (BL) exploit antigen-independent tonic signals transduced by the B-cell antigen receptor (BCR) for their survival, but the molecular details of the rewired BL-specific BCR signal network remain...
10.
Pham T, Perumal N, Manicam C, Basoglu M, Eimer S, Fuhrmann D, et al.
Redox Biol
. 2023 Oct;
67:102943.
PMID: 37883843
Accumulation of misfolded proteins or perturbation of calcium homeostasis leads to endoplasmic reticulum (ER) stress and is linked to the pathogenesis of neurodegenerative diseases. Hence, understanding the ability of neuronal...