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Seung-Yong Seo

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Articles 75
Citations 571
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Recent Articles
11.
Wook Lee J, Gu H, Jung Y, Jung Y, Seo S, Hong J, et al.
Exp Mol Med . 2023 Apr; 55(5):910-925. PMID: 37121975
Insulin resistance is a major contributor to the pathogenesis of several human diseases, including type 2 diabetes, hypertension, and hyperlipidemia. Notably, insulin resistance and hypertension share common abnormalities, including increased...
12.
Shin C, Lee S, Jin H, Fei X, Kang S, Seo S, et al.
Biochem Pharmacol . 2023 Apr; 211:115534. PMID: 37019186
Dry age-related macular degeneration (AMD) is a type of disease that causes visual impairment due to changes in the macula located in the center of the retina. The accumulation of...
13.
Choi Y, Huh E, Lee S, Kim J, Park M, Seo S, et al.
Biomol Ther (Seoul) . 2023 Mar; 31(4):402-410. PMID: 36918741
Long-term administration of levodopa (L-DOPA) to patients with Parkinson's disease (PD) commonly results in involuntary dyskinetic movements, as is known for L-DOPA-induced dyskinesia (LID). 5-Hydroxytryptophan (5-HTP) has recently been shown...
14.
Kwon S, Lee S, Hur J, Ko K, Fei X, Jeong K, et al.
J Nat Prod . 2022 Dec; 86(1):149-156. PMID: 36542352
Dracaeconolide B (), a naturally occurring homoisoflavane, was isolated from the red resin of . Efforts have been made to elucidate the exact structure of compound since it was confirmed...
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Kim E, Lee B, Kwon S, Corson T, Seo S, Lee K
Pharmaceutics . 2022 Nov; 14(11). PMID: 36365089
Cremastranone is a member of the homoisoflavanone family with anti-angiogenic activity in the eyes. SH-11037, a potent and selective synthetic homoisoflavonoid derived from cremastranone, was studied here for pharmacokinetics and...
17.
Shin H, Lee S, Choi Y, Park S, Kwon S, Choi J, et al.
Biomol Ther (Seoul) . 2022 Aug; 30(6):576-584. PMID: 35934668
Colorectal cancer is diagnosed as the third most prevalent cancer; thus, effective therapeutic agents are urgently required. In this study, we synthesized six homoisoflavane derivatives of cremastranone and investigated their...
18.
Jo M, Moon C, Kim E, Kwon J, Fei X, Kim S, et al.
BMC Cancer . 2022 Mar; 22(1):341. PMID: 35351071
Background: Since colon cancer stem cells (CSCs) play an important role in chemoresistance and in tumor recurrence and metastasis, targeting of CSCs has emerged as a sophisticated strategy for cancer...
19.
Sishtla K, Lambert-Cheatham N, Lee B, Han D, Park J, Sardar Pasha S, et al.
Cell Chem Biol . 2022 Jan; 29(6):1010-1023.e14. PMID: 35090600
Activity of the heme synthesis enzyme ferrochelatase (FECH) is implicated in multiple diseases. In particular, it is a mediator of neovascularization in the eye and thus an appealing therapeutic target...
20.
Kim O, Kang G, Hur J, Lee J, Jung Y, Hong I, et al.
Cell Death Differ . 2022 Jan; 29(7):1423-1432. PMID: 35017647
Apoptotic cells are rapidly engulfed and removed by phagocytes after displaying cell surface eat-me signals. Among many phospholipids, only phosphatidylserine (PS) is known to act as an eat-me signal on...