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Sergei V Strelkov

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Articles 97
Citations 2684
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Recent Articles
1.
Vermeire P, Lilina A, Hashim H, Dlabolova L, Fiala J, Beelen S, et al.
Sci Rep . 2024 Nov; 14(1):28721. PMID: 39567589
No abstract available.
2.
Vantieghem T, Aslam N, Osipov E, Akele M, Van Belle S, Beelen S, et al.
Eur J Med Chem . 2024 Oct; 280:116960. PMID: 39461037
Lens epithelium-derived growth factor p75 (LEDGF/p75), member of the hepatoma-derived growth-factor-related protein (HRP) family, is a transcriptional co-activator and involved in several pathologies including HIV infection and malignancies such as...
3.
Bondue T, Cervellini F, Smeets B, Strelkov S, Horuz-Engels F, Veys K, et al.
J Cell Physiol . 2024 Sep; 239(12):e31447. PMID: 39319391
Renal proximal tubular reabsorption of proteins and polypeptides is tightly regulated by a concerted action of the multi-ligand receptors with subsequent processing from the clathrin-coated pits to early/recycling and late...
4.
Smiejkowska N, Oorts L, Van Calster K, De Vooght L, Geens R, Mattelaer H, et al.
Microbiol Spectr . 2024 Feb; 12(3):e0372323. PMID: 38315026
Importance: The growing anti-microbial resistance poses a global public health threat, impeding progress toward eradicating tuberculosis. Despite decades of active research, there is still a dire need for the discovery...
5.
Vermeire P, Lilina A, Hashim H, Dlabolova L, Fiala J, Beelen S, et al.
Sci Rep . 2023 May; 13(1):8841. PMID: 37258554
Intermediate filaments (IFs) are essential constituents of the metazoan cytoskeleton. A vast family of cytoplasmic IF proteins are capable of self-assembly from soluble tetrameric species into typical 10-12 nm wide...
6.
Chistov A, Chumakov S, Mikhnovets I, Nikitin T, Slesarchuk N, Uvarova V, et al.
Antiviral Res . 2022 Dec; 209:105508. PMID: 36581049
Amphipathic nucleoside and non-nucleoside derivatives of pentacyclic aromatic hydrocarbon perylene are known as potent non-cytotoxic broad-spectrum antivirals. Here we report 3-methyl-5-(perylen-3-ylethynyl)-uracil-1-acetic acid and its amides, a new series of compounds...
7.
Pang L, Lenders S, Osipov E, Weeks S, Rozenski J, Piller T, et al.
Int J Mol Sci . 2022 Dec; 23(23). PMID: 36499418
Mycothiol (MSH), the major cellular thiol in (Mtb), plays an essential role in the resistance of Mtb to various antibiotics and oxidative stresses. MshC catalyzes the ATP-dependent ligation of 1--(2-amino-2-deoxy-α-d-glucopyranosyl)-d--inositol...
8.
Lilina A, Leekens S, Hashim H, Vermeire P, Harvey J, Strelkov S
Protein Sci . 2022 Nov; 31(12):e4505. PMID: 36369679
Intermediate filaments (IFs) form an essential part of the metazoan cytoskeleton. Despite a long history of research, a proper understanding of their molecular architecture and assembly process is still lacking....
9.
Pang L, Zanki V, Strelkov S, Van Aerschot A, Gruic-Sovulj I, Weeks S
Commun Biol . 2022 Aug; 5(1):883. PMID: 36038645
To correctly aminoacylate tRNA, leucyl-tRNA synthetase (LeuRS) catalyzes three reactions: activation of leucine by ATP to form leucyl-adenylate (Leu-AMP), transfer of this amino acid to tRNA and post-transfer editing of...
10.
Osipov E, Munawar A, Beelen S, Fearon D, Douangamath A, Wild C, et al.
RSC Chem Biol . 2022 Aug; 3(8):1013-1027. PMID: 35974998
Polyomaviruses are a family of ubiquitous double-stranded DNA viruses many of which are human pathogens. These include BK polyomavirus which causes severe urinary tract infection in immunocompromised patients and Merkel...