Serge J Smeets
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Explore the profile of Serge J Smeets including associated specialties, affiliations and a list of published articles.
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15
Citations
497
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Recent Articles
1.
Franke N, Kaspers G, Assaraf Y, Van Meerloo J, Niewerth D, Kessler F, et al.
Oncotarget
. 2016 Aug;
7(46):74779-74796.
PMID: 27542283
PSMB5 mutations and upregulation of the β5 subunit of the proteasome represent key determinants of acquired resistance to the proteasome inhibitor bortezomib (BTZ) in leukemic cells in vitro. We here...
2.
Krijgsman O, Israeli D, Haan J, van Essen H, Smeets S, Eijk P, et al.
Genes Chromosomes Cancer
. 2011 Dec;
51(4):344-52.
PMID: 22162309
Formalin-fixed, paraffin-embedded (FFPE) archival tissue is an important source of DNA material. The most commonly used technique to identify copy number aberrations from chromosomal DNA in tumorigenesis is array comparative...
3.
Smeets S, Harjes U, van Wieringen W, Sie D, Brakenhoff R, Meijer G, et al.
Clin Cancer Res
. 2011 Jun;
17(15):4959-64.
PMID: 21673065
Genome-wide RNA expression profiling has yielded tumor subtypes with strong predictive or prognostic value for a wide variety of cancers. Recently, for breast cancer two RNA expression classifiers have been...
4.
Smeets S, van der Plas M, Schaaij-Visser T, van Veen E, Van Meerloo J, Braakhuis B, et al.
Int J Cancer
. 2010 May;
128(7):1596-605.
PMID: 20499310
A subgroup of head and neck squamous cell carcinomas (HNSCCs) contains high-risk human papillomavirus-type 16 (HPV16). The viral E6 and E7 oncoproteins inactivate the p53 and pRb proteins, respectively. We...
5.
Bossers K, Ylstra B, Brakenhoff R, Smeets S, Verhaagen J, van de Wiel M
BMC Genomics
. 2010 Feb;
11:112.
PMID: 20163706
Background: Ratio-based analysis is the current standard for the analysis of dual-color microarray data. Indeed, this method provides a powerful means to account for potential technical variations such as differences...
6.
Smeets S, Brakenhoff R, Ylstra B, van Wieringen W, van de Wiel M, Leemans C, et al.
Cell Oncol
. 2009 Jul;
31(4):291-300.
PMID: 19633365
The common risk factors for oral and oropharyngeal cancer are tobacco smoking and alcohol consumption, and recently the human papillomavirus (HPV) was shown to be involved in a subgroup. HPV-positive...
7.
Wilting S, Smeets S, Snijders P, van Wieringen W, van de Wiel M, Meijer G, et al.
BMC Med Genomics
. 2009 Jun;
2:32.
PMID: 19486517
Background: It is well known that a persistent infection with high-risk human papillomavirus (hrHPV) is causally involved in the development of squamous cell carcinomas of the uterine cervix (CxSCCs) and...
8.
Schaaij-Visser T, Brakenhoff R, Jansen J, OFlaherty M, Smeets S, Heck A, et al.
J Proteomics
. 2009 May;
72(5):803-14.
PMID: 19446051
The 5-year-survival rate of head and neck squamous cell carcinoma (HNSCC) has been only moderately improved over the last few decades. HNSCC develops in precursor fields of genetically altered mucosal...
9.
Oudejans J, van Wieringen W, Smeets S, Tijssen M, Vosse S, Meijer C, et al.
Genes Chromosomes Cancer
. 2008 Dec;
48(3):250-60.
PMID: 19051311
Diffuse large B-cell lymphomas (DLBCL) are highly heterogeneous with regard to clinical presentation and outcome. DLBCL copy number aberrations have been identified previously, of which the deletion at 6q21-24 was...
10.
Zafrakas M, Tarlatzis B, Streichert T, Pournaropoulos F, Wolfle U, Smeets S, et al.
Int J Mol Med
. 2008 Feb;
21(3):335-44.
PMID: 18288381
The aim of the present study was to investigate whether endometriosis and cancer share common molecular characteristics. Tissue samples were collected prospectively during diagnostic laparoscopy of patients with primary infertility....