C Rene Leemans
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Explore the profile of C Rene Leemans including associated specialties, affiliations and a list of published articles.
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399
Citations
14629
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Recent Articles
1.
Muijlwijk T, Nauta I, van der Lee A, Grunewald K, Brink A, Ganzevles S, et al.
Nat Commun
. 2025 Feb;
16(1):1705.
PMID: 39962066
No abstract available.
2.
Jansen F, Eerenstein S, Arman S, Lissenberg-Witte B, Hardillo J, Takes R, et al.
JAMA Otolaryngol Head Neck Surg
. 2025 Feb;
PMID: 39913126
Importance: Adverse effects of cancer and its treatment may hamper return to work (RTW) among patients with head and neck cancer (HNC). Objectives: To investigate RTW among patients with HNC...
3.
Nauta I, Nijenhuis D, Ganzevles S, Raaff P, Kloosterman J, Bloemena E, et al.
Cancers (Basel)
. 2025 Jan;
17(1.
PMID: 39796740
Background/objectives: Most studies on the interaction between the immune system and cancer focus on T-cells, whereas studies on tumor-infiltrating B-lymphocytes (TIL-Bs) are still underrepresented. The aim of this study was...
4.
Homan E, Kwakkenbos L, Deuning-Smit E, Jansen F, Verdonck-de Leeuw I, Takes R, et al.
J Cancer Surviv
. 2024 Dec;
PMID: 39680304
Purpose: Limited data exists on the long-term course of fear of cancer recurrence (FCR) in head and neck cancer (HNC) patients. One in five patients was found to experience persistent...
5.
Muijlwijk T, Nauta I, van der Lee A, Grunewald K, Brink A, Ganzevles S, et al.
Nat Commun
. 2024 Oct;
15(1):9060.
PMID: 39428388
Cancer is caused by an accumulation of somatic mutations and copy number alterations (CNAs). Besides mutations, these copy number changes are key characteristics of cancer development. Nonetheless, some tumors show...
6.
von Buchwald C, Jakobsen K, Fenger Carlander A, Tous S, Gronhoj C, Rasmussen J, et al.
Eur J Cancer
. 2024 Sep;
211:114329.
PMID: 39293346
Purpose: The assessment of p16INK4a (p16) in oropharyngeal squamous cell carcinoma (OPSCC) has been incorporated into tumor classification, as p16 has been shown to impact survival probability. However, a recent...
7.
Muijlwijk T, Wondergem N, Ekhlas F, Remkes N, Nijenhuis D, Fritz L, et al.
Cancer Immunol Immunother
. 2024 Sep;
73(11):229.
PMID: 39249543
Immune checkpoint inhibitors are approved for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) but the response rate is only 13-18%. For an effective antitumor immune response, trafficking of immune...
8.
Muijlwijk T, Nijenhuis D, Ganzevles S, Ekhlas F, Ballesteros-Merino C, Peferoen L, et al.
J Immunother Cancer
. 2024 Jul;
12(7).
PMID: 39053947
Background: Approximately 50% of head and neck squamous cell carcinomas (HNSCC) recur after treatment with curative intent. Immune checkpoint inhibitors are treatment options for recurrent/metastatic HNSCC; however, less than 20%...
9.
Wondergem N, Miedema I, van de Ven R, Zwezerijnen G, de Graaf P, Karagozoglu K, et al.
J Immunother Cancer
. 2024 Jul;
12(7).
PMID: 39038919
Background: Addition of neoadjuvant immune checkpoint inhibition to standard-of-care interventions for locally advanced oral cancer could improve clinical outcome. Methods: In this study, 16 evaluable patients with stage III/IV oral...
10.
van der Scheer F, Jansen F, Eerenstein S, Vergeer M, Leemans C, Verdonck-de Leeuw I, et al.
Oral Dis
. 2024 Jul;
30(8):4830-4837.
PMID: 38988121
Objectives: Robotic transoral mucosectomy of the base of tongue was introduced as a diagnostic procedure in patients treated for head and neck cancer with unknown primary (CUP), increasing the identification...