Serena Spudich
Overview
Explore the profile of Serena Spudich including associated specialties, affiliations and a list of published articles.
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135
Citations
5468
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Recent Articles
1.
Chan P, Li X, Li F, Emu B, Price R, Spudich S
Front Immunol
. 2025 Mar;
16:1531828.
PMID: 40070827
Background: Trafficking of immune cells to the central nervous system is hypothesized to facilitate HIV entry and immune-induced neuronal injury and is mediated by surface proteins such as chemokine receptors...
2.
Yang J, Agrawal K, Stanley 3rd J, Stanley J, Li R, Jacobs N, et al.
bioRxiv
. 2025 Feb;
PMID: 39975288
HIV infection exerts profound and long-lasting neurodegenerative effects on the central nervous system (CNS) that can persist despite antiretroviral therapy (ART). Here, we used single-nucleus multiome sequencing to map the...
3.
Ocampo F, Sacdalan C, Pinyakorn S, Paudel M, Wansom T, Poltubtim N, et al.
AIDS Res Ther
. 2025 Feb;
22(1):20.
PMID: 39972347
Background: Hepatitis C virus (HCV) coinfection may further compromise immunological and cognitive function in people with HIV (PWH). This study compared laboratory and neuropsychiatric measures across the periods of HCV...
4.
Kincer L, Dravid A, Trunfio M, Calcagno A, Zhou S, Vercesi R, et al.
J Clin Invest
. 2024 Oct;
134(19).
PMID: 39352388
During antiretroviral therapy (ART), most people living with HIV-1 have undetectable HIV-1 RNA in their plasma. However, they occasionally present with new or progressive neurologic deficits and detectable HIV-1 RNA...
5.
Patel P, Prince D, Bolenzius J, Chen P, Chiarella J, Kolind S, et al.
AIDS
. 2024 Aug;
38(14):1932-1939.
PMID: 39110577
Objective: Approximately 40% of adults living with HIV experience cognitive deficits. Little is known about the risk factors for cognitive impairment and its association with myelin content in young adults...
6.
Chan P, Spudich S
Viruses
. 2024 Jul;
16(7).
PMID: 39066244
HIV infection is a multi-organ disease that involves the central nervous system (CNS). While devastating CNS complications such as HIV-associated dementia and CNS opportunistic infection typically manifest years after HIV...
7.
Pluvinage J, Ngo T, Fouassier C, McDonagh M, Holmes B, Bartley C, et al.
Sci Transl Med
. 2024 Jun;
16(753):eadl3758.
PMID: 38924428
Vitamin B12 is critical for hematopoiesis and myelination. Deficiency can cause neurologic deficits including loss of coordination and cognitive decline. However, diagnosis relies on measurement of vitamin B12 in the...
8.
Ament S, Campbell R, Lobo M, Receveur J, Agrawal K, Borjabad A, et al.
Mol Psychiatry
. 2024 Jun;
29(12):3950-3961.
PMID: 38879719
Substance use disorders (SUD) and drug addiction are major threats to public health, impacting not only the millions of individuals struggling with SUD, but also surrounding families and communities. One...
9.
Wagner T, Tierney C, Huang S, Nichols S, Malee K, Montanez N, et al.
AIDS
. 2024 May;
38(10):1494-1504.
PMID: 38814693
Objective: Central nervous system (CNS) HIV infection can impact cognition and may be an obstacle to cure in adolescents and young adults with perinatal HIV (AYAPHIV). IMPAACT2015 enrolled AYAPHIV on...
10.
Ocampo F, Sacdalan C, Pinyakorn S, Paudel M, Wansom T, Poltubtim N, et al.
Res Sq
. 2024 Apr;
PMID: 38645141
Background: Hepatitis C virus (HCV) coinfection may further compromise immunological and cognitive function in people with HIV (PWH). This study compared laboratory and neuropsychiatric measures across the periods of HCV...